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Patients undergo image-guided intensity-modulated radiation therapy using helical tomotherapy on days -8 to -5.\n\nTRANSPLANTATION: Patients undergo allogeneic peripheral blood stem cell transplantation or bone marrow transplantation on day 0.\n\nGRAFT-VS-HOST DISEASE (GVHD) PROPHYLAXIS: Patients receive GVHD prophylaxis that excludes methotrexate.\n\nbusulfan: Given IV\n\netoposide: Given IV\n\nintensity-modulated radiation therapy: Initially 150 cGy X 8 doses with gradual dose escalation to 200 cGy X 10 doses\n\nallogeneic hematopoietic stem cell transplantation: Stem cell transplantation occurs on Day 0 after High Dose Therapy\n\nallogeneic bone marrow transplantation: Stem cell transplantation occurs on Day 0 after High Dose Therapy\n\nperipheral blood stem cell transplantation: Stem cell transplantation occurs on Day 0 after High Dose Therapy\n\ntomotherapy: Initially 150 cGy X 8 doses with gradual dose escalation to 200 cGy X 10 doses","id":"EG000","otherNumAffected":23,"otherNumAtRisk":23,"seriousNumAffected":7,"seriousNumAtRisk":23,"title":"Arm I: 1200cGy"},{"deathsNumAffected":2,"deathsNumAtRisk":2,"description":"1350cGy = 150cGy x 9 doses: Patients receive busulfan IV once daily over 2 hours on days -15 and -13 and then every 6 hours on days -12 to -9. 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(3.0)","stats":[{"groupId":"EG000","numAffected":8,"numAtRisk":23,"numEvents":8},{"groupId":"EG001","numAffected":0,"numAtRisk":2,"numEvents":0}],"term":"Fever (in the absence of neutropenia, ANC <1.0 x 10e9/L)"},{"assessmentType":"SYSTEMATIC_ASSESSMENT","organSystem":"General disorders","sourceVocabulary":"CTCAE (3.0)","stats":[{"groupId":"EG000","numAffected":18,"numAtRisk":23,"numEvents":18},{"groupId":"EG001","numAffected":0,"numAtRisk":2,"numEvents":0}],"term":"Insomnia"},{"assessmentType":"SYSTEMATIC_ASSESSMENT","organSystem":"General disorders","sourceVocabulary":"CTCAE (3.0)","stats":[{"groupId":"EG000","numAffected":16,"numAtRisk":23,"numEvents":16},{"groupId":"EG001","numAffected":2,"numAtRisk":2,"numEvents":2}],"term":"Rigors/chills"},{"assessmentType":"SYSTEMATIC_ASSESSMENT","organSystem":"General disorders","sourceVocabulary":"CTCAE 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(3.0)","stats":[{"groupId":"EG000","numAffected":0,"numAtRisk":23,"numEvents":0},{"groupId":"EG001","numAffected":1,"numAtRisk":2,"numEvents":1}],"term":"Mucositis/stomatitis (functional/symptomatic)"},{"assessmentType":"SYSTEMATIC_ASSESSMENT","organSystem":"Infections and infestations","sourceVocabulary":"CTCAE (3.0)","stats":[{"groupId":"EG000","numAffected":1,"numAtRisk":23,"numEvents":1},{"groupId":"EG001","numAffected":0,"numAtRisk":2,"numEvents":0}],"term":"Colitis, infectious (e.g., Clostridium difficile)"},{"assessmentType":"SYSTEMATIC_ASSESSMENT","organSystem":"Infections and infestations","sourceVocabulary":"CTCAE (3.0)","stats":[{"groupId":"EG000","numAffected":1,"numAtRisk":23,"numEvents":1},{"groupId":"EG001","numAffected":0,"numAtRisk":2,"numEvents":0}],"term":"Febrile neutropenia (ANC <1.0 x 10e9/L, fever >=38.5 degrees C)"},{"assessmentType":"SYSTEMATIC_ASSESSMENT","organSystem":"Infections and infestations","sourceVocabulary":"CTCAE (3.0)","stats":[{"groupId":"EG000","numAffected":2,"numAtRisk":23,"numEvents":2},{"groupId":"EG001","numAffected":0,"numAtRisk":2,"numEvents":0}],"term":"Infection with Grade 3 or 4 neutrophils (ANC <1.0 x 10e9/L)"},{"assessmentType":"SYSTEMATIC_ASSESSMENT","organSystem":"Respiratory, thoracic and mediastinal disorders","sourceVocabulary":"CTCAE (3.0)","stats":[{"groupId":"EG000","numAffected":1,"numAtRisk":23,"numEvents":1},{"groupId":"EG001","numAffected":0,"numAtRisk":2,"numEvents":0}],"term":"Adult Respiratory Distress Syndrome (ARDS)"},{"assessmentType":"SYSTEMATIC_ASSESSMENT","organSystem":"Investigations","sourceVocabulary":"CTCAE (3.0)","stats":[{"groupId":"EG000","numAffected":1,"numAtRisk":23,"numEvents":1},{"groupId":"EG001","numAffected":0,"numAtRisk":2,"numEvents":0}],"term":"Syndromes - Other (Specify, __)"}],"timeFrame":"Adverse events were captured from initial treatment to Day 180 post-transplant. Vital Statuses were captured from the initial treatment to death."}