{"analyses":[{"ciNumSides":"TWO_SIDED","groupDescription":"Log-rank test. (Mantel-Haenszel test). Null hypothesis is all four groups are statistically from the same population. Alternative hypothesis is that at least one of the groups is from a population different from the remaining groups. Anticipated sample-sizes comparing Active ALL (anticipated N= 12) with the combined AML patients (anticipated N=38) was deemed to be too small for formal hypothesis testing.","groupIds":["OG000","OG001","OG002","OG003"],"nonInferiorityComment":"Given the small sample-size of the disease sub-groups, this was a hypothesis generating study.","nonInferiorityType":"EQUIVALENCE","pValue":">0.05","pValueComment":"Not adjusted for multiple comparisons. A-priori threshold for statistical significance was 0.05.","paramType":"Median Difference (Net)","paramValue":"0","statisticalComment":"No adjustments.","statisticalMethod":"Log Rank"}],"classes":[{"categories":[{"measurements":[{"groupId":"OG000","lowerLimit":"20","upperLimit":"90","value":"67"},{"groupId":"OG001","lowerLimit":"11","upperLimit":"80","value":"50"},{"groupId":"OG002","lowerLimit":"7","upperLimit":"38","value":"30"},{"groupId":"OG003","lowerLimit":"5","upperLimit":"38","value":"33"}]}]}],"denoms":[{"counts":[{"groupId":"OG000","value":"6"},{"groupId":"OG001","value":"6"},{"groupId":"OG002","value":"10"},{"groupId":"OG003","value":"6"}],"units":"Participants"}],"description":"Kaplan-Meier estimate of an event of death estimated at five years post-transplant. 95% confidence intervals were calculated from the logit transform of the Greenwood variance. The transformation was necessary to keep the estimate within the probability space of 0 to 100%.","dispersionType":"95% Confidence Interval","groups":[{"description":"Acute Myelogenous Leukemia Transplanted in First Complete Remission","id":"OG000","title":"AML/1CR"},{"description":"Acute Myelogenous Leukemia Transplanted in First Relapse","id":"OG001","title":"AML/R1"},{"description":"Acute Myelogenous Leukemia Transplanted in Induction Failure","id":"OG002","title":"AML/IF"},{"description":"Active Acute Lymphocytic Leukemia","id":"OG003","title":"Active ALL"}],"paramType":"NUMBER","populationDescription":"Study cohort separated into four disease groups.","reportingStatus":"POSTED","timeFrame":"Date of Transplant to Five Years post-Transplant","title":"Overall Survival Comparing Diagnosis Groups","type":"PRIMARY","unitOfMeasure":"percentage of survival probability"}