{"classes":[{"categories":[{"measurements":[{"groupId":"OG000","spread":"13.541","value":"-3.00"},{"groupId":"OG001","spread":"12.296","value":"-2.36"}]}],"title":"SBP, Week 1, n=246, 491"},{"categories":[{"measurements":[{"groupId":"OG000","spread":"13.800","value":"-3.25"},{"groupId":"OG001","spread":"13.122","value":"-3.74"}]}],"title":"SBP, Week 2, n=242, 494"},{"categories":[{"measurements":[{"groupId":"OG000","spread":"13.781","value":"-3.75"},{"groupId":"OG001","spread":"13.780","value":"-3.91"}]}],"title":"SBP, Week 4, n=228, 485"},{"categories":[{"measurements":[{"groupId":"OG000","spread":"14.405","value":"-3.36"},{"groupId":"OG001","spread":"14.624","value":"-3.85"}]}],"title":"SBP, Week 6, n=206, 471"},{"categories":[{"measurements":[{"groupId":"OG000","spread":"14.073","value":"-2.72"},{"groupId":"OG001","spread":"14.401","value":"-4.33"}]}],"title":"SBP, Week 8, n=190, 472"},{"categories":[{"measurements":[{"groupId":"OG000","spread":"15.297","value":"-2.16"},{"groupId":"OG001","spread":"14.377","value":"-4.30"}]}],"title":"SBP, Week 12, n=175, 452"},{"categories":[{"measurements":[{"groupId":"OG000","spread":"15.426","value":"-3.16"},{"groupId":"OG001","spread":"13.579","value":"-4.59"}]}],"title":"SBP, Week 16, n=143, 403"},{"categories":[{"measurements":[{"groupId":"OG000","spread":"14.387","value":"-2.50"},{"groupId":"OG001","spread":"14.908","value":"-4.12"}]}],"title":"SBP, Week 20, n=133, 374"},{"categories":[{"measurements":[{"groupId":"OG000","spread":"14.820","value":"-1.97"},{"groupId":"OG001","spread":"14.917","value":"-3.94"}]}],"title":"SBP, Week 24, n=99, 263"},{"categories":[{"measurements":[{"groupId":"OG000","spread":"14.663","value":"-0.69"},{"groupId":"OG001","spread":"14.557","value":"-4.99"}]}],"title":"SBP, Week 28, n=74, 211"},{"categories":[{"measurements":[{"groupId":"OG000","spread":"13.904","value":"-1.46"},{"groupId":"OG001","spread":"13.523","value":"-5.61"}]}],"title":"SBP, Week 32, n=67, 197"},{"categories":[{"measurements":[{"groupId":"OG000","spread":"13.803","value":"-1.31"},{"groupId":"OG001","spread":"14.842","value":"-4.40"}]}],"title":"SBP, Week 36, n=62, 186"},{"categories":[{"measurements":[{"groupId":"OG000","spread":"13.605","value":"0.10"},{"groupId":"OG001","spread":"13.941","value":"-4.31"}]}],"title":"SBP, Week 40, n=59, 173"},{"categories":[{"measurements":[{"groupId":"OG000","spread":"11.689","value":"0.56"},{"groupId":"OG001","spread":"13.794","value":"-4.54"}]}],"title":"SBP, Week 44, n=59, 167"},{"categories":[{"measurements":[{"groupId":"OG000","spread":"13.259","value":"-2.03"},{"groupId":"OG001","spread":"15.318","value":"-3.98"}]}],"title":"SBP, End of Treatment, n=238, 468"},{"categories":[{"measurements":[{"groupId":"OG000","spread":"14.095","value":"-1.14"},{"groupId":"OG001","spread":"15.122","value":"-1.65"}]}],"title":"SBP, 4-week FU, n=221, 426"},{"categories":[{"measurements":[{"groupId":"OG000","spread":"14.113","value":"-0.11"},{"groupId":"OG001","spread":"14.806","value":"-0.86"}]}],"title":"SBP, 12-week FU, n=207, 432"},{"categories":[{"measurements":[{"groupId":"OG000","spread":"14.545","value":"1.10"},{"groupId":"OG001","spread":"14.518","value":"0.25"}]}],"title":"SBP, 24-week FU, n=203, 398"},{"categories":[{"measurements":[{"groupId":"OG000","spread":"9.235","value":"-1.43"},{"groupId":"OG001","spread":"8.224","value":"-1.37"}]}],"title":"DBP, Week 1, n=246, 491"},{"categories":[{"measurements":[{"groupId":"OG000","spread":"9.217","value":"-1.55"},{"groupId":"OG001","spread":"8.946","value":"-1.86"}]}],"title":"DBP, Week 2, n=242, 493"},{"categories":[{"measurements":[{"groupId":"OG000","spread":"9.726","value":"-1.84"},{"groupId":"OG001","spread":"9.467","value":"-2.72"}]}],"title":"DBP, Week 4, n=228, 485"},{"categories":[{"measurements":[{"groupId":"OG000","spread":"8.939","value":"-2.16"},{"groupId":"OG001","spread":"9.859","value":"-2.95"}]}],"title":"DBP, Week 6, n=206, 471"},{"categories":[{"measurements":[{"groupId":"OG000","spread":"9.517","value":"-1.24"},{"groupId":"OG001","spread":"9.901","value":"-2.68"}]}],"title":"DBP, Week 8, n=190, 472"},{"categories":[{"measurements":[{"groupId":"OG000","spread":"8.781","value":"-1.31"},{"groupId":"OG001","spread":"10.025","value":"-3.23"}]}],"title":"DBP, Week 12, n=175, 452"},{"categories":[{"measurements":[{"groupId":"OG000","spread":"9.684","value":"-1.54"},{"groupId":"OG001","spread":"9.899","value":"-3.31"}]}],"title":"DBP, Week 16, n=143, 403"},{"categories":[{"measurements":[{"groupId":"OG000","spread":"10.582","value":"-0.93"},{"groupId":"OG001","spread":"9.606","value":"-3.08"}]}],"title":"DBP, Week 20, n=133, 374"},{"categories":[{"measurements":[{"groupId":"OG000","spread":"10.207","value":"-1.66"},{"groupId":"OG001","spread":"9.313","value":"-3.54"}]}],"title":"DBP, Week 24, n=99, 263"},{"categories":[{"measurements":[{"groupId":"OG000","spread":"9.538","value":"-1.23"},{"groupId":"OG001","spread":"10.502","value":"-3.42"}]}],"title":"DBP, Week 28, n=74, 211"},{"categories":[{"measurements":[{"groupId":"OG000","spread":"10.445","value":"-0.54"},{"groupId":"OG001","spread":"9.527","value":"-3.76"}]}],"title":"DBP, Week 32, n=67, 197"},{"categories":[{"measurements":[{"groupId":"OG000","spread":"9.559","value":"-0.74"},{"groupId":"OG001","spread":"9.211","value":"-3.59"}]}],"title":"DBP, Week 36, n=62, 186"},{"categories":[{"measurements":[{"groupId":"OG000","spread":"9.343","value":"0.34"},{"groupId":"OG001","spread":"9.517","value":"-3.32"}]}],"title":"DBP, Week 40, n=59, 173"},{"categories":[{"measurements":[{"groupId":"OG000","spread":"9.033","value":"0.92"},{"groupId":"OG001","spread":"10.134","value":"-3.77"}]}],"title":"DBP, Week 44, n=59, 167"},{"categories":[{"measurements":[{"groupId":"OG000","spread":"9.174","value":"-1.55"},{"groupId":"OG001","spread":"10.254","value":"-3.59"}]}],"title":"DBP, End of Treatment, n=238, 468"},{"categories":[{"measurements":[{"groupId":"OG000","spread":"9.102","value":"-0.83"},{"groupId":"OG001","spread":"9.824","value":"-2.20"}]}],"title":"DBP, 4-week FU, n=221, 426"},{"categories":[{"measurements":[{"groupId":"OG000","spread":"10.253","value":"-0.78"},{"groupId":"OG001","spread":"9.903","value":"-1.76"}]}],"title":"DBP, 12-week FU, n=207, 432"},{"categories":[{"measurements":[{"groupId":"OG000","spread":"9.814","value":"0.03"},{"groupId":"OG001","spread":"9.339","value":"-1.61"}]}],"title":"DBP, 24-week FU, n=203, 398"}],"denoms":[{"counts":[{"groupId":"OG000","value":"246"},{"groupId":"OG001","value":"494"}],"units":"Participants"}],"description":"Participant's blood pressure was measured at the indicated time points during the study. Systolic blood pressure is a measure of blood pressure while the heart is beating. Diastolic blood pressure is a measure of blood pressure while the heart is relaxed. Mean change from Baseline was calculated as the value at the indicated time points minus the value at Baseline.","dispersionType":"Standard Deviation","groups":[{"description":"Participants completing the OL Phase were administered matching placebo tablets QD in combination with antiviral therapy (peginterferon alfa-2b and ribavirin) for a duration of either 24 or 48 weeks (for participants with Genotype 2/3) or 48 weeks (for participants with Non-Genotype 2/3).","id":"OG000","title":"Placebo+Antiviral Therapy: DB Phase"},{"description":"Participants completing the OL Phase continued on the same dose of eltrombopag received in the OL Phase (dose that effectively raised platelets to \\>=100 Gi/L) in combination with antiviral therapy (peginterferon alfa-2b and ribavirin) for a duration of either 24 or 48 weeks (for participants with Genotype 2/3) or 48 weeks (for participants with Non-Genotype 2/3).","id":"OG001","title":"Eltrombopag+Antiviral Therapy: DB Phase"}],"paramType":"MEAN","populationDescription":"Safety DB Population. Only those participants contributing data at the indicated time points were analyzed.","reportingStatus":"POSTED","timeFrame":"DB Phase: Baseline; Weeks 1, 2, 4, 6, 8, 12, 16, 20, 24, 28, 32, 36, 40, and 44; End of Treatment (up to Week 48); 4-week Follow-up (FU) (up to Week 52); 12-week FU (up to Week 60); and 24-week FU (up to Week 72)","title":"Mean Change From Baseline in Systolic Blood Pressure (SBP) and Diastolic Blood Pressure (DBP) at the Indicated Time Points During the DB Phase","type":"SECONDARY","unitOfMeasure":"Millimeters of mercury (mmHg)"}