{"classes":[{"categories":[{"measurements":[{"groupId":"OG000","spread":"25.48","value":"58.1"},{"groupId":"OG001","spread":"27.39","value":"58.7"}]}],"title":"Worst Pain"},{"categories":[{"measurements":[{"groupId":"OG000","spread":"20.28","value":"78.0"},{"groupId":"OG001","spread":"22.01","value":"77.3"}]}],"title":"Least Pain"},{"categories":[{"measurements":[{"groupId":"OG000","spread":"21.99","value":"66.4"},{"groupId":"OG001","spread":"24.55","value":"65.4"}]}],"title":"Average Pain"},{"categories":[{"measurements":[{"groupId":"OG000","spread":"20.16","value":"76.5"},{"groupId":"OG001","spread":"21.16","value":"77.3"}]}],"title":"BPI Total Interference"}],"denoms":[{"counts":[{"groupId":"OG000","value":"101"},{"groupId":"OG001","value":"102"}],"units":"Participants"}],"description":"Pain severity, defined by the four items addressing worst, least, and average pain and pain right now as measured by the BPI will be analyzed identical to the primary endpoint. Additionally, total pain interference as measured by the BPI will be transformed onto a 0-100 ( higher is less pain) point scale. The area under the curve (AUC) from baseline to week 4 was calculated for each patient's score. The average AUC for the placebo arm and the topical amitriptyline HCl/ baclofen/ ketamine arm are reported.","dispersionType":"Standard Deviation","groups":[{"description":"Patients apply 1 spoonful of baclofen-amitriptyline hydrochloride-ketamine gel topically to each area of pain, numbness, and/or tingling on the feet and/or hands twice daily for 4 weeks. Baclofen/amitriptyline/ketamine gel: Applied topically.","id":"OG000","title":"Baclofen-amitriptyline Hydrochloride-ketamine"},{"description":"Patients apply 1 spoonful of placebo gel topically to each area of pain, numbness, and/or tingling on the feet and/or hands twice daily for 4 weeks. Placebo: Applied topically","id":"OG001","title":"Placebo"}],"paramType":"MEAN","reportingStatus":"POSTED","timeFrame":"Up to 4 weeks","title":"Pain Severity and Interference as Measured by the Brief Pain Inventory (BPI) at Baseline and Week 4","type":"SECONDARY","unitOfMeasure":"units on a scale * week"}