{"classes":[{"categories":[{"measurements":[{"groupId":"OG000","lowerLimit":"90.0","upperLimit":"96.8","value":"94.4"},{"groupId":"OG001","lowerLimit":"86.8","upperLimit":"95.0","value":"91.8"}]}],"title":"Month 3"},{"categories":[{"measurements":[{"groupId":"OG000","lowerLimit":"85.2","upperLimit":"94.0","value":"90.6"},{"groupId":"OG001","lowerLimit":"79.3","upperLimit":"91.0","value":"86.3"}]}],"title":"Month 6"}],"denoms":[{"counts":[{"groupId":"OG000","value":"207"},{"groupId":"OG001","value":"203"}],"units":"Participants"}],"description":"Time to definitive worsening is defined as a definitive increase in performance status from a baseline of 0 or 1 to WHO \\>= 2, or from a baseline value of 2 to WHO \\>= 3. If no earlier deterioration, patients were censored at the end of follow-up or at the start of further antineoplastic therapy. Rates of patients with no deterioration at 3 and 6 months were computed using Kaplan-meier method. Grade 0: Able to carry out all activity without restriction; Grade 1: Restricted in physically strenuous activity but ambulatory \\& able to do light work; Grade 2: Ambulatory \\& capable of all self-care but unable to carry out any work. Up \\& about more than 50% of waking hours; Grade 3: Capable of only limited self-care, confined to bed or chair more than 50% of waking hours; Grade 4: Completely disabled \\& cannot carry on any self-care; totally confined to bed or chair.","groups":[{"description":"Participants received 10 mg per day of everolimus plus best supportive care. Patients received their first dose of everolimus at Visit 2 (Cycle 1 Day 1).","id":"OG000","title":"Everolimus 10 mg/Day"},{"description":"Participants received matching placebo to everolimus daily plus best supportive care. Patients received their first dose of matching placebo at Visit 2 (Cycle 1 Day 1).","id":"OG001","title":"Placebo"}],"paramType":"NUMBER","populationDescription":"The Full Analysis Set (FAS) consists of all patients who were randomized.","reportingStatus":"POSTED","timeFrame":"3 months, 6 months","title":"Analysis of Time to Definitive Deterioration of WHO Performance Status Using Kaplan-Meier","type":"SECONDARY","unitOfMeasure":"% of participants with no deterioration"}