{"classes":[{"categories":[{"measurements":[{"groupId":"OG000","value":"5"}]}]}],"denoms":[{"counts":[{"groupId":"OG000","value":"5"}],"units":"Participants"}],"description":"The secondary objective of this study is to assess the safely and tolerability of the combination treatment of bevacizumnab and bortezomnib. Adjustments in the dosing schedule of bortezomib would be made for patients with adequate response as per Blade criteria and continue until disease progression or 18 months","groups":[{"description":"Bortezomilb will be administered at 1.3 mglm2 IVP on Days 1. 4, 8, and 11. Response will be assessed subsequent to each cycle. A total of 8 cycles would beplanned. Patients would be removed subsequent to Cycle 2. if progression of disease is documented.","id":"OG000","title":"Bortezomilb and Bevacizumab"}],"paramType":"NUMBER","reportingStatus":"POSTED","timeFrame":"18 months","title":"Overall Survival (OS) - Number of Participants Alive at Study Completion","type":"PRIMARY","unitOfMeasure":"participants"}