{"classes":[{"categories":[{"measurements":[{"groupId":"OG000","spread":"15.03","value":"141.8"}]}],"title":"Baseline (n=6)"},{"categories":[{"measurements":[{"groupId":"OG000","spread":"17.05","value":"144.2"}]}],"title":"Infusion (0 minutes) (n=5)"},{"categories":[{"measurements":[{"groupId":"OG000","spread":"22.90","value":"154.3"}]}],"title":"21 minutes post infusion (n=6)"},{"categories":[{"measurements":[{"groupId":"OG000","spread":"14.71","value":"140.3"}]}],"title":"36 minutes post infusion (n=6)"},{"categories":[{"measurements":[{"groupId":"OG000","spread":"10.05","value":"147.5"}]}],"title":"51 minutes post infusion (n=6)"},{"categories":[{"measurements":[{"groupId":"OG000","spread":"15.44","value":"141.0"}]}],"title":"66 minutes post infusion (n=6)"},{"categories":[{"measurements":[{"groupId":"OG000","spread":"17.60","value":"145.7"}]}],"title":"82 minutes post infusion (n=6)"},{"categories":[{"measurements":[{"groupId":"OG000","spread":"16.29","value":"141.8"}]}],"title":"97 minutes post infusion (n=6)"},{"categories":[{"measurements":[{"groupId":"OG000","spread":"11.55","value":"139.8"}]}],"title":"112 minutes post infusion (n=6)"},{"categories":[{"measurements":[{"groupId":"OG000","spread":"20.47","value":"140.3"}]}],"title":"127 minutes post infusion (n=6)"},{"categories":[{"measurements":[{"groupId":"OG000","spread":"7.78","value":"137.5"}]}],"title":"157 minutes post infusion (n=2)"},{"categories":[{"measurements":[{"groupId":"OG000","spread":"8.04","value":"139.3"}]}],"title":"1 hour post infusion (n=6)"},{"categories":[{"measurements":[{"groupId":"OG000","spread":"20.85","value":"145.8"}]}],"title":"2 hour post infusion (n=6)"},{"categories":[{"measurements":[{"groupId":"OG000","spread":"7.92","value":"140.3"}]}],"title":"3 hour post infusion (n=6)"},{"categories":[{"measurements":[{"groupId":"OG000","spread":"9.89","value":"139.8"}]}],"title":"4 hour post infusion (n=6)"},{"categories":[{"measurements":[{"groupId":"OG000","spread":"19.06","value":"142.8"}]}],"title":"6 hour post infusion (n=6)"},{"categories":[{"measurements":[{"groupId":"OG000","spread":"12.77","value":"145.5"}]}],"title":"8 hour post infusion (n=6)"}],"denoms":[{"counts":[{"groupId":"OG000","value":"6"}],"units":"Participants"}],"description":"Systolic blood pressures (SBPs) measured in millimeters of mercury (mmHg) were obtained while the participant was seated. Baseline, Infusion (0 minutes) and Post infusion SBPs are presented in the 0.3 mg cohort at: 21, 36, 51, 66, 82, 97, 112, 127, 157 minutes post infusion, and at 1, 2, 3, 4, 6, 8 hours post infusion. Baseline was defined as the last measurement before the first dose of study drug, which was calculated from pre-dose or from screening if pre-dose was not available. Mean SBP on Day 1 for first dose (cycle 1) are presented below.","dispersionType":"Standard Deviation","groups":[{"description":"0.3 mg of nivolumab per kg of body weight (mg/kg) was administered in a single IV infusion on Day 1 with 10% of the dose infused over 6 minutes and after a 1 hour observation period, the balance was administered over 60 minutes. Eligible participants could be re-treated and receive 2 more doses (1 dose every 4 weeks) at same dose as the single dose if: disease was stable, no drug intolerance was observed, no CR or PR was observed, or they had a positive immunogenicity sample within 4 weeks prior to re-treatment. Those who responded to therapy with a CR or PR were eligible for long-term follow-up until either PD or 2 years elapsed.","id":"OG000","title":"0.3 mg/kg Nivolumab"}],"paramType":"MEAN","populationDescription":"All participants who received at least 1 dose or any partial dose of nivolumab and had available blood pressure at baseline and post-infusion were analyzed.","reportingStatus":"POSTED","timeFrame":"Baseline, Day 1","title":"Mean Systolic Blood Pressure at Baseline and Post-Infusion Day 1 (Cycle 1) in 0.3 mg Cohort - Safety Population","type":"SECONDARY","unitOfMeasure":"mmHg"}