{"classes":[{"categories":[{"measurements":[{"groupId":"OG000","value":"29"}]}],"title":"Hemoglobin, any grade increase, n=78"},{"categories":[{"measurements":[{"groupId":"OG000","value":"2"}]}],"title":"Hemoglobin, increase to Grade 3, n=78"},{"categories":[{"measurements":[{"groupId":"OG000","value":"0"}]}],"title":"Hemoglobin, increas to Grade 4, n=78"},{"categories":[{"measurements":[{"groupId":"OG000","value":"10"}]}],"title":"INR (PT), any grade increase, n=67"},{"categories":[{"measurements":[{"groupId":"OG000","value":"2"}]}],"title":"INR (PT), increase to Grade 3, n=67"},{"categories":[{"measurements":[{"groupId":"OG000","value":"0"}]}],"title":"INR (PT), increase to Grade 4, n=67"},{"categories":[{"measurements":[{"groupId":"OG000","value":"34"}]}],"title":"Lymphocytes, any grade increase, n=78"},{"categories":[{"measurements":[{"groupId":"OG000","value":"7"}]}],"title":"Lymphocytes, increase to Grade 3, n=78"},{"categories":[{"measurements":[{"groupId":"OG000","value":"2"}]}],"title":"Lymphocytes, increase to Grade 4, n=78"},{"categories":[{"measurements":[{"groupId":"OG000","value":"29"}]}],"title":"Neutrophils, any grade increase, n=78"},{"categories":[{"measurements":[{"groupId":"OG000","value":"1"}]}],"title":"Neutrophils, increase to Grade 3, n=78"},{"categories":[{"measurements":[{"groupId":"OG000","value":"1"}]}],"title":"Neutrophils, increase to Grade 4, n=78"},{"categories":[{"measurements":[{"groupId":"OG000","value":"31"}]}],"title":"Platelets, any grade increase, n=78"},{"categories":[{"measurements":[{"groupId":"OG000","value":"1"}]}],"title":"Platelets, increase to Grade 3, n=78"},{"categories":[{"measurements":[{"groupId":"OG000","value":"0"}]}],"title":"Platelets, increase to Grade 4, n=78"},{"categories":[{"measurements":[{"groupId":"OG000","value":"32"}]}],"title":"WBC, any grade increase, n=78"},{"categories":[{"measurements":[{"groupId":"OG000","value":"2"}]}],"title":"WBC, increase to Grade 3, n=78"},{"categories":[{"measurements":[{"groupId":"OG000","value":"0"}]}],"title":"WBC, increase to Grade 4, n=78"}],"denoms":[{"counts":[{"groupId":"OG000","value":"80"}],"units":"Participants"}],"description":"Hematology parameters were summarized according to NIH CTCAE, version 4.0. Grade 1, mild; Grade 2, moderate; Grade 3, severe; Grade 4, life-threatening or disabling; Grade 5, death. Data are presented for only those parameters for which an increase from Baseline occurred. Hematology parameters included: hemoglobin (anemia), lymphocytes (lymphocytopenia), neutrophils (neutropenia), platelets (thrombocytopenia), white blood cells (WBC \\[leukopenia\\]), and prothrombin time international normalized ratio (PT \\[INR\\]). Participants with missing Baseline grades are assumed to have a Baseline grade of 0.","groups":[{"description":"Participants received pazopanib 800 milligrams (mg) once daily.","id":"OG000","title":"Pazopanib 800 mg"}],"paramType":"NUMBER","populationDescription":"ATS Population. Only those participants available at the specified time points were analyzed (represented by n=X in the category titles). Different participants may have been analyzed for different parameters, so the overall number of participants analyzed reflects everyone in the ATS Population.","reportingStatus":"POSTED","timeFrame":"From Baseline to investigational product discontinuation (up to 6.230 years)","title":"Number of Participants With the Indicated Worst-case Grade Increase From Baseline for the Indicated Hematology Parameters at Any Time Post-Baseline","type":"PRIMARY","unitOfMeasure":"participants"}