{"denoms":[{"counts":[{"groupId":"BG000","value":"18"},{"groupId":"BG001","value":"28"},{"groupId":"BG002","value":"46"}],"units":"Participants"}],"groups":[{"description":"Subjects will receive transplant conditioning with Ara-C, Cyclophosphamide, Campath-1H, Total Body Irradiation and will then receive T cell depleted stem cell infusion processed by the CLINIMACS Device\n\nAra-C: day-8 through day-5\n\n3 g/m2 q 12 hours\n\nCyclophosphamide: day-7 and day-6\n\n45 mg/kg\n\nCampath-1H: day-3 through day-1\n\nDosing for children:\n\n5 - 15kg : 3mg IV in 30ml NS\n\n15.1 - 30kg : 5mg IV in 50ml NS\n\n\\>30 kg : 10mg IV in 100ml NS\n\nAdults will receive 10mg IV in 100ml NS\n\nTotal Body Irradiation: day-4 through day-1\n\n175 cGy x 2 at 24 cGy/min\n\nStem Cell Infusion: Stem cells are infused on day 0","id":"BG000","title":"CLINIMACS Device"},{"description":"Subjects will receive transplant conditioning with Ara-C, Cyclophosphamide, Campath-1H, Total Body Irradiation and will then receive T cell depleted stem cell infusion processed by the ISOLEX Device\n\nAra-C: day-8 through day-5\n\n3 g/m2 q 12 hours\n\nCyclophosphamide: day-7 and day-6\n\n45 mg/kg\n\nCampath-1H: day-3 through day-1\n\nDosing for children:\n\n5 - 15kg : 3mg IV in 30ml NS\n\n15.1 - 30kg : 5mg IV in 50ml NS\n\n\\>30 kg : 10mg IV in 100ml NS\n\nAdults will receive 10mg IV in 100ml NS\n\nTotal Body Irradiation: day-4 through day-1\n\n175 cGy x 2 at 24 cGy/min\n\nStem Cell Infusion: Stem cells are infused on day 0","id":"BG001","title":"ISOLEX Device"},{"description":"Total of all reporting groups","id":"BG002","title":"Total"}],"measures":[{"classes":[{"categories":[{"measurements":[{"groupId":"BG000","lowerLimit":"5","upperLimit":"13","value":"7"},{"groupId":"BG001","lowerLimit":"2.5","upperLimit":"11","value":"7"},{"groupId":"BG002","lowerLimit":"3","upperLimit":"12","value":"7"}]}]}],"dispersionType":"INTER_QUARTILE_RANGE","paramType":"MEDIAN","title":"Age, Continuous","unitOfMeasure":"years"},{"classes":[{"categories":[{"measurements":[{"groupId":"BG000","value":"7"},{"groupId":"BG001","value":"9"},{"groupId":"BG002","value":"16"}],"title":"Female"},{"measurements":[{"groupId":"BG000","value":"11"},{"groupId":"BG001","value":"19"},{"groupId":"BG002","value":"30"}],"title":"Male"}]}],"paramType":"COUNT_OF_PARTICIPANTS","title":"Sex: Female, Male","unitOfMeasure":"Participants"},{"classes":[{"categories":[{"measurements":[{"groupId":"BG000","value":"2"},{"groupId":"BG001","value":"5"},{"groupId":"BG002","value":"7"}]}],"title":"White"},{"categories":[{"measurements":[{"groupId":"BG000","value":"3"},{"groupId":"BG001","value":"8"},{"groupId":"BG002","value":"11"}]}],"title":"Black or African American"},{"categories":[{"measurements":[{"groupId":"BG000","value":"1"},{"groupId":"BG001","value":"1"},{"groupId":"BG002","value":"2"}]}],"title":"Asian"},{"categories":[{"measurements":[{"groupId":"BG000","value":"12"},{"groupId":"BG001","value":"14"},{"groupId":"BG002","value":"26"}]}],"title":"Hispanic or Latino"}],"paramType":"COUNT_OF_PARTICIPANTS","title":"Race/Ethnicity, Customized","unitOfMeasure":"Participants"}],"populationDescription":"Participants who had their donor stem cells processed using the ISOLEX or CliniMACS CD34 Reagent System and started preparative regimen were included in this analysis."}