{"description":"Anticipated \"other than serious\" Allogeneic Hematopoietic Cell Transplantation (HCT) adverse events were not tabulated.","eventGroups":[{"description":"Busulfan targeted area under the curve, level 1: 6000 +/- 600 uM-min","id":"EG000","otherNumAffected":0,"otherNumAtRisk":40,"seriousNumAffected":2,"seriousNumAtRisk":40,"title":"AUC Level 1"},{"description":"Busulfan targeted area under the curve, level 2: 7500 +/- 750 uM-min","id":"EG001","otherNumAffected":0,"otherNumAtRisk":29,"seriousNumAffected":13,"seriousNumAtRisk":29,"title":"AUC Level 2"},{"description":"Busulfan targeted area under the curve, level 3: 9000 +/- 900 uM-min","id":"EG002","otherNumAffected":0,"otherNumAtRisk":3,"seriousNumAffected":2,"seriousNumAtRisk":3,"title":"AUC Level 3"}],"frequencyThreshold":"5","seriousEvents":[{"assessmentType":"NON_SYSTEMATIC_ASSESSMENT","notes":"Unlikely to be related","organSystem":"Cardiac disorders","sourceVocabulary":"CTCAE (3.0)","stats":[{"groupId":"EG000","numAffected":0,"numAtRisk":40,"numEvents":0},{"groupId":"EG001","numAffected":1,"numAtRisk":29,"numEvents":1},{"groupId":"EG002","numAffected":0,"numAtRisk":3,"numEvents":0}],"term":"Cardiac ischemia/infarction"},{"assessmentType":"NON_SYSTEMATIC_ASSESSMENT","notes":"Unlikely to be related","organSystem":"Gastrointestinal disorders","sourceVocabulary":"CTCAE (3.0)","stats":[{"groupId":"EG000","numAffected":0,"numAtRisk":40,"numEvents":0},{"groupId":"EG001","numAffected":1,"numAtRisk":29,"numEvents":1},{"groupId":"EG002","numAffected":1,"numAtRisk":3,"numEvents":1}],"term":"Hemorrhage, GI - 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Other, VOD"},{"assessmentType":"NON_SYSTEMATIC_ASSESSMENT","organSystem":"Hepatobiliary disorders","sourceVocabulary":"CTCAE (3.0)","stats":[{"groupId":"EG000","numAffected":0,"numAtRisk":40,"numEvents":0},{"groupId":"EG001","numAffected":1,"numAtRisk":29,"numEvents":1},{"groupId":"EG002","numAffected":1,"numAtRisk":3,"numEvents":1}],"term":"Liver dysfunction/failure (clinical)"},{"assessmentType":"NON_SYSTEMATIC_ASSESSMENT","organSystem":"Infections and infestations","sourceVocabulary":"CTCAE (3.0)","stats":[{"groupId":"EG000","numAffected":0,"numAtRisk":40,"numEvents":0},{"groupId":"EG001","numAffected":1,"numAtRisk":29,"numEvents":1},{"groupId":"EG002","numAffected":0,"numAtRisk":3,"numEvents":0}],"term":"Infection with normal ANC or Grade 1 or 2 neutrophils - Bladder (urinary)"},{"assessmentType":"NON_SYSTEMATIC_ASSESSMENT","notes":"Unrelated","organSystem":"Infections and infestations","sourceVocabulary":"CTCAE (3.0)","stats":[{"groupId":"EG000","numAffected":0,"numAtRisk":40,"numEvents":0},{"groupId":"EG001","numAffected":1,"numAtRisk":29,"numEvents":1},{"groupId":"EG002","numAffected":0,"numAtRisk":3,"numEvents":0}],"term":"Infection with normal ANC or Grade 1 or 2 neutrophils - Blood"},{"assessmentType":"NON_SYSTEMATIC_ASSESSMENT","notes":"Unrelated","organSystem":"Infections and infestations","sourceVocabulary":"CTCAE (3.0)","stats":[{"groupId":"EG000","numAffected":0,"numAtRisk":40,"numEvents":0},{"groupId":"EG001","numAffected":3,"numAtRisk":29,"numEvents":4},{"groupId":"EG002","numAffected":0,"numAtRisk":3,"numEvents":0}],"term":"Infection with normal ANC or Grade 1 or 2 neutrophils - Lung (pneumonia)"},{"assessmentType":"NON_SYSTEMATIC_ASSESSMENT","notes":"Unrelated","organSystem":"Infections and infestations","sourceVocabulary":"CTCAE (3.0)","stats":[{"groupId":"EG000","numAffected":0,"numAtRisk":40,"numEvents":0},{"groupId":"EG001","numAffected":1,"numAtRisk":29,"numEvents":1},{"groupId":"EG002","numAffected":0,"numAtRisk":3,"numEvents":0}],"term":"Infection with normal ANC or Grade 1 or 2 neutrophils - Stomach"},{"assessmentType":"NON_SYSTEMATIC_ASSESSMENT","notes":"Unrelated","organSystem":"Metabolism and nutrition disorders","sourceVocabulary":"CTCAE (3.0)","stats":[{"groupId":"EG000","numAffected":1,"numAtRisk":40,"numEvents":1},{"groupId":"EG001","numAffected":0,"numAtRisk":29,"numEvents":0},{"groupId":"EG002","numAffected":0,"numAtRisk":3,"numEvents":0}],"term":"AST, SGOT - high"},{"assessmentType":"NON_SYSTEMATIC_ASSESSMENT","notes":"Unrelated","organSystem":"Nervous system disorders","sourceVocabulary":"CTCAE (3.0)","stats":[{"groupId":"EG000","numAffected":0,"numAtRisk":40,"numEvents":0},{"groupId":"EG001","numAffected":1,"numAtRisk":29,"numEvents":1},{"groupId":"EG002","numAffected":0,"numAtRisk":3,"numEvents":0}],"term":"Cognitive disturbance"},{"assessmentType":"NON_SYSTEMATIC_ASSESSMENT","notes":"Unrelated","organSystem":"Psychiatric disorders","sourceVocabulary":"CTCAE (3.0)","stats":[{"groupId":"EG000","numAffected":1,"numAtRisk":40,"numEvents":1},{"groupId":"EG001","numAffected":0,"numAtRisk":29,"numEvents":0},{"groupId":"EG002","numAffected":0,"numAtRisk":3,"numEvents":0}],"term":"Mental status"},{"assessmentType":"NON_SYSTEMATIC_ASSESSMENT","notes":"Unrelated","organSystem":"Respiratory, thoracic and mediastinal disorders","sourceVocabulary":"CTCAE (3.0)","stats":[{"groupId":"EG000","numAffected":0,"numAtRisk":40,"numEvents":0},{"groupId":"EG001","numAffected":1,"numAtRisk":29,"numEvents":1},{"groupId":"EG002","numAffected":0,"numAtRisk":3,"numEvents":0}],"term":"Adult Respiratory Distress Syndrome (ARDS)"},{"assessmentType":"NON_SYSTEMATIC_ASSESSMENT","notes":"Unrelated","organSystem":"Respiratory, thoracic and mediastinal disorders","sourceVocabulary":"CTCAE (3.0)","stats":[{"groupId":"EG000","numAffected":0,"numAtRisk":40,"numEvents":0},{"groupId":"EG001","numAffected":1,"numAtRisk":29,"numEvents":1},{"groupId":"EG002","numAffected":0,"numAtRisk":3,"numEvents":0}],"term":"Hemorrhage, pulmonary/upper respiratory - Lung"},{"assessmentType":"NON_SYSTEMATIC_ASSESSMENT","notes":"Unrelated","organSystem":"Respiratory, thoracic and mediastinal disorders","sourceVocabulary":"CTCAE (3.0)","stats":[{"groupId":"EG000","numAffected":0,"numAtRisk":40,"numEvents":0},{"groupId":"EG001","numAffected":1,"numAtRisk":29,"numEvents":1},{"groupId":"EG002","numAffected":0,"numAtRisk":3,"numEvents":0}],"term":"Pulmonary/Upper Respiratory - Other, edema"}]}