{"classes":[{"categories":[{"measurements":[{"groupId":"OG000","spread":"47.8","value":"350.0"},{"groupId":"OG001","spread":"1664.5","value":"2806.7"},{"groupId":"OG002","spread":"872.0","value":"15181.2"},{"groupId":"OG003","spread":"5350.8","value":"40428.4"}]}],"title":"Cmax"},{"categories":[{"measurements":[{"groupId":"OG000","spread":"7.4","value":"158.2"},{"groupId":"OG001","spread":"1873.4","value":"1515.2"},{"groupId":"OG002","spread":"872.9","value":"6824.7"},{"groupId":"OG003","spread":"4264.7","value":"19516.8"}]}],"title":"Ctrough"}],"denoms":[{"counts":[{"groupId":"OG000","value":"3"},{"groupId":"OG001","value":"4"},{"groupId":"OG002","value":"3"},{"groupId":"OG003","value":"6"}],"units":"Participants"}],"description":"Plasma KW-0761 concentrations were to be summarized in tabular form with the descriptive statistics on a dose-by-dose basis. Individual and mean (+ standard deviation) plasma KW-0761 concentrations on an actual or logarithmic scale were to be plotted against the time of blood sampling.","dispersionType":"Standard Deviation","groups":[{"description":"IV infusions of KW-0761 once/week for 4 weeks","id":"OG000","title":"KW-0761 0.01mg"},{"description":"IV infusions of KW-0761 once/week for 4 weeks","id":"OG001","title":"KW-0761 0.1mg"},{"description":"IV infusions of KW-0761 once/week for 4 weeks","id":"OG002","title":"KW-0761 0.5mg"},{"description":"IV infusions of KW-0761 once/week for 4 weeks","id":"OG003","title":"KW-0761 1.0mg"}],"paramType":"MEAN","reportingStatus":"POSTED","timeFrame":"0-7 days post final dose","title":"Pharmacokinetics-Plasma KW-0761 Concentrations","type":"PRIMARY","unitOfMeasure":"ng/mL"}