{"eventGroups":[{"description":"IV infusions of KW-0761 once/week for 4 weeks","id":"EG000","otherNumAffected":3,"otherNumAtRisk":3,"seriousNumAffected":1,"seriousNumAtRisk":3,"title":"KW-0761 0.01mg"},{"description":"IV infusions of KW-0761 once/week for 4 weeks","id":"EG001","otherNumAffected":4,"otherNumAtRisk":4,"seriousNumAffected":1,"seriousNumAtRisk":4,"title":"KW-0761 0.1mg"},{"description":"IV infusions of KW-0761 once/week for 4 weeks","id":"EG002","otherNumAffected":3,"otherNumAtRisk":3,"seriousNumAffected":0,"seriousNumAtRisk":3,"title":"KW-0761 0.5mg"},{"description":"IV infusions of KW-0761 once/week for 4 weeks","id":"EG003","otherNumAffected":6,"otherNumAtRisk":6,"seriousNumAffected":1,"seriousNumAtRisk":6,"title":"KW-0761 1.0mg"}],"frequencyThreshold":"5","otherEvents":[{"organSystem":"Blood and lymphatic system disorders","sourceVocabulary":"MedDRA (11.1)","stats":[{"groupId":"EG000","numAffected":0,"numAtRisk":3,"numEvents":0},{"groupId":"EG001","numAffected":0,"numAtRisk":4,"numEvents":0},{"groupId":"EG002","numAffected":0,"numAtRisk":3,"numEvents":0},{"groupId":"EG003","numAffected":1,"numAtRisk":6,"numEvents":1}],"term":"Febrile neutropenia"},{"organSystem":"Blood and lymphatic system disorders","sourceVocabulary":"MedDRA (11.1)","stats":[{"groupId":"EG000","numAffected":0,"numAtRisk":3,"numEvents":0},{"groupId":"EG001","numAffected":0,"numAtRisk":4,"numEvents":0},{"groupId":"EG002","numAffected":0,"numAtRisk":3,"numEvents":0},{"groupId":"EG003","numAffected":1,"numAtRisk":6,"numEvents":1}],"term":"Lymph node pain"},{"organSystem":"Cardiac disorders","sourceVocabulary":"MedDRA (11.1)","stats":[{"groupId":"EG000","numAffected":0,"numAtRisk":3,"numEvents":0},{"groupId":"EG001","numAffected":3,"numAtRisk":4,"numEvents":3},{"groupId":"EG002","numAffected":0,"numAtRisk":3,"numEvents":0},{"groupId":"EG003","numAffected":0,"numAtRisk":6,"numEvents":0}],"term":"Tachycardia"},{"organSystem":"Cardiac disorders","sourceVocabulary":"MedDRA (11.1)","stats":[{"groupId":"EG000","numAffected":2,"numAtRisk":3,"numEvents":2},{"groupId":"EG001","numAffected":0,"numAtRisk":4,"numEvents":0},{"groupId":"EG002","numAffected":0,"numAtRisk":3,"numEvents":0},{"groupId":"EG003","numAffected":1,"numAtRisk":6,"numEvents":1}],"term":"Left ventricular dysfunction"},{"organSystem":"Gastrointestinal disorders","sourceVocabulary":"MedDRA (11.1)","stats":[{"groupId":"EG000","numAffected":1,"numAtRisk":3,"numEvents":1},{"groupId":"EG001","numAffected":0,"numAtRisk":4,"numEvents":0},{"groupId":"EG002","numAffected":0,"numAtRisk":3,"numEvents":0},{"groupId":"EG003","numAffected":0,"numAtRisk":6,"numEvents":0}],"term":"Constipation"},{"organSystem":"Gastrointestinal disorders","sourceVocabulary":"MedDRA (11.1)","stats":[{"groupId":"EG000","numAffected":1,"numAtRisk":3,"numEvents":1},{"groupId":"EG001","numAffected":0,"numAtRisk":4,"numEvents":0},{"groupId":"EG002","numAffected":0,"numAtRisk":3,"numEvents":0},{"groupId":"EG003","numAffected":0,"numAtRisk":6,"numEvents":0}],"term":"Nausea"},{"organSystem":"General disorders","sourceVocabulary":"MedDRA (11.1)","stats":[{"groupId":"EG000","numAffected":0,"numAtRisk":3,"numEvents":0},{"groupId":"EG001","numAffected":0,"numAtRisk":4,"numEvents":0},{"groupId":"EG002","numAffected":0,"numAtRisk":3,"numEvents":0},{"groupId":"EG003","numAffected":2,"numAtRisk":6,"numEvents":2}],"term":"Chills"},{"organSystem":"General disorders","sourceVocabulary":"MedDRA (11.1)","stats":[{"groupId":"EG000","numAffected":1,"numAtRisk":3,"numEvents":1},{"groupId":"EG001","numAffected":1,"numAtRisk":4,"numEvents":1},{"groupId":"EG002","numAffected":1,"numAtRisk":3,"numEvents":1},{"groupId":"EG003","numAffected":1,"numAtRisk":6,"numEvents":1}],"term":"Fatigue"},{"organSystem":"General disorders","sourceVocabulary":"MedDRA (11.1)","stats":[{"groupId":"EG000","numAffected":0,"numAtRisk":3,"numEvents":0},{"groupId":"EG001","numAffected":0,"numAtRisk":4,"numEvents":0},{"groupId":"EG002","numAffected":1,"numAtRisk":3,"numEvents":1},{"groupId":"EG003","numAffected":0,"numAtRisk":6,"numEvents":0}],"term":"Malaise"},{"organSystem":"General disorders","sourceVocabulary":"MedDRA (11.1)","stats":[{"groupId":"EG000","numAffected":1,"numAtRisk":3,"numEvents":1},{"groupId":"EG001","numAffected":0,"numAtRisk":4,"numEvents":0},{"groupId":"EG002","numAffected":2,"numAtRisk":3,"numEvents":2},{"groupId":"EG003","numAffected":1,"numAtRisk":6,"numEvents":1}],"term":"Pyrexia"},{"organSystem":"General disorders","sourceVocabulary":"MedDRA (11.1)","stats":[{"groupId":"EG000","numAffected":3,"numAtRisk":3,"numEvents":3},{"groupId":"EG001","numAffected":3,"numAtRisk":4,"numEvents":3},{"groupId":"EG002","numAffected":3,"numAtRisk":3,"numEvents":3},{"groupId":"EG003","numAffected":4,"numAtRisk":6,"numEvents":4}],"term":"Infusion-related reaction"},{"organSystem":"Immune system disorders","sourceVocabulary":"MedDRA (11.1)","stats":[{"groupId":"EG000","numAffected":0,"numAtRisk":3,"numEvents":0},{"groupId":"EG001","numAffected":1,"numAtRisk":4,"numEvents":1},{"groupId":"EG002","numAffected":0,"numAtRisk":3,"numEvents":0},{"groupId":"EG003","numAffected":0,"numAtRisk":6,"numEvents":0}],"term":"Cytokine release syndrome"},{"organSystem":"Infections and infestations","sourceVocabulary":"MedDRA (11.1)","stats":[{"groupId":"EG000","numAffected":1,"numAtRisk":3,"numEvents":1},{"groupId":"EG001","numAffected":0,"numAtRisk":4,"numEvents":0},{"groupId":"EG002","numAffected":0,"numAtRisk":3,"numEvents":0},{"groupId":"EG003","numAffected":0,"numAtRisk":6,"numEvents":0}],"term":"Nasopharyngitis"},{"organSystem":"Infections and infestations","sourceVocabulary":"MedDRA (11.1)","stats":[{"groupId":"EG000","numAffected":1,"numAtRisk":3,"numEvents":1},{"groupId":"EG001","numAffected":0,"numAtRisk":4,"numEvents":0},{"groupId":"EG002","numAffected":0,"numAtRisk":3,"numEvents":0},{"groupId":"EG003","numAffected":0,"numAtRisk":6,"numEvents":0}],"term":"Skin infection"},{"organSystem":"Investigations","sourceVocabulary":"MedDRA (11.1)","stats":[{"groupId":"EG000","numAffected":1,"numAtRisk":3,"numEvents":1},{"groupId":"EG001","numAffected":1,"numAtRisk":4,"numEvents":1},{"groupId":"EG002","numAffected":0,"numAtRisk":3,"numEvents":0},{"groupId":"EG003","numAffected":2,"numAtRisk":6,"numEvents":2}],"term":"Alanine aminotransferase increased"},{"organSystem":"Investigations","sourceVocabulary":"MedDRA (11.1)","stats":[{"groupId":"EG000","numAffected":1,"numAtRisk":3,"numEvents":1},{"groupId":"EG001","numAffected":1,"numAtRisk":4,"numEvents":1},{"groupId":"EG002","numAffected":0,"numAtRisk":3,"numEvents":0},{"groupId":"EG003","numAffected":2,"numAtRisk":6,"numEvents":2}],"term":"Aspartate aminotransferase increased"},{"organSystem":"Investigations","sourceVocabulary":"MedDRA (11.1)","stats":[{"groupId":"EG000","numAffected":0,"numAtRisk":3,"numEvents":0},{"groupId":"EG001","numAffected":1,"numAtRisk":4,"numEvents":1},{"groupId":"EG002","numAffected":1,"numAtRisk":3,"numEvents":1},{"groupId":"EG003","numAffected":0,"numAtRisk":6,"numEvents":0}],"term":"Blood albumin decreased"},{"organSystem":"Investigations","sourceVocabulary":"MedDRA (11.1)","stats":[{"groupId":"EG000","numAffected":0,"numAtRisk":3,"numEvents":0},{"groupId":"EG001","numAffected":0,"numAtRisk":4,"numEvents":0},{"groupId":"EG002","numAffected":1,"numAtRisk":3,"numEvents":1},{"groupId":"EG003","numAffected":2,"numAtRisk":6,"numEvents":2}],"term":"Blood lactate dehydrogenase increased"},{"organSystem":"Investigations","sourceVocabulary":"MedDRA (11.1)","stats":[{"groupId":"EG000","numAffected":0,"numAtRisk":3,"numEvents":0},{"groupId":"EG001","numAffected":1,"numAtRisk":4,"numEvents":1},{"groupId":"EG002","numAffected":1,"numAtRisk":3,"numEvents":1},{"groupId":"EG003","numAffected":1,"numAtRisk":6,"numEvents":1}],"term":"Blood pressure increased"},{"organSystem":"Investigations","sourceVocabulary":"MedDRA (11.1)","stats":[{"groupId":"EG000","numAffected":0,"numAtRisk":3,"numEvents":0},{"groupId":"EG001","numAffected":0,"numAtRisk":4,"numEvents":0},{"groupId":"EG002","numAffected":1,"numAtRisk":3,"numEvents":1},{"groupId":"EG003","numAffected":0,"numAtRisk":6,"numEvents":0}],"term":"Blood sodium increased"},{"organSystem":"Investigations","sourceVocabulary":"MedDRA (11.1)","stats":[{"groupId":"EG000","numAffected":1,"numAtRisk":3,"numEvents":1},{"groupId":"EG001","numAffected":0,"numAtRisk":4,"numEvents":0},{"groupId":"EG002","numAffected":0,"numAtRisk":3,"numEvents":0},{"groupId":"EG003","numAffected":1,"numAtRisk":6,"numEvents":1}],"term":"Electrocardiogram QT prolonged"},{"organSystem":"Investigations","sourceVocabulary":"MedDRA (11.1)","stats":[{"groupId":"EG000","numAffected":1,"numAtRisk":3,"numEvents":1},{"groupId":"EG001","numAffected":0,"numAtRisk":4,"numEvents":0},{"groupId":"EG002","numAffected":0,"numAtRisk":3,"numEvents":0},{"groupId":"EG003","numAffected":0,"numAtRisk":6,"numEvents":0}],"term":"Blood urine present"},{"organSystem":"Investigations","sourceVocabulary":"MedDRA (11.1)","stats":[{"groupId":"EG000","numAffected":0,"numAtRisk":3,"numEvents":0},{"groupId":"EG001","numAffected":0,"numAtRisk":4,"numEvents":0},{"groupId":"EG002","numAffected":0,"numAtRisk":3,"numEvents":0},{"groupId":"EG003","numAffected":1,"numAtRisk":6,"numEvents":1}],"term":"Haemoglobin decreased"},{"organSystem":"Investigations","sourceVocabulary":"MedDRA (11.1)","stats":[{"groupId":"EG000","numAffected":0,"numAtRisk":3,"numEvents":0},{"groupId":"EG001","numAffected":0,"numAtRisk":4,"numEvents":0},{"groupId":"EG002","numAffected":0,"numAtRisk":3,"numEvents":0},{"groupId":"EG003","numAffected":1,"numAtRisk":6,"numEvents":1}],"term":"Heart rate increased"},{"organSystem":"Investigations","sourceVocabulary":"MedDRA (11.1)","stats":[{"groupId":"EG000","numAffected":2,"numAtRisk":3,"numEvents":2},{"groupId":"EG001","numAffected":4,"numAtRisk":4,"numEvents":4},{"groupId":"EG002","numAffected":3,"numAtRisk":3,"numEvents":3},{"groupId":"EG003","numAffected":6,"numAtRisk":6,"numEvents":6}],"term":"Lymphocyte count decreased"},{"organSystem":"Investigations","sourceVocabulary":"MedDRA (11.1)","stats":[{"groupId":"EG000","numAffected":1,"numAtRisk":3,"numEvents":1},{"groupId":"EG001","numAffected":2,"numAtRisk":4,"numEvents":2},{"groupId":"EG002","numAffected":3,"numAtRisk":3,"numEvents":3},{"groupId":"EG003","numAffected":4,"numAtRisk":6,"numEvents":4}],"term":"Neutrophil count decreased"},{"organSystem":"Investigations","sourceVocabulary":"MedDRA (11.1)","stats":[{"groupId":"EG000","numAffected":0,"numAtRisk":3,"numEvents":0},{"groupId":"EG001","numAffected":1,"numAtRisk":4,"numEvents":1},{"groupId":"EG002","numAffected":0,"numAtRisk":3,"numEvents":0},{"groupId":"EG003","numAffected":0,"numAtRisk":6,"numEvents":0}],"term":"Neutrophil count increased"},{"organSystem":"Investigations","sourceVocabulary":"MedDRA (11.1)","stats":[{"groupId":"EG000","numAffected":3,"numAtRisk":3,"numEvents":3},{"groupId":"EG001","numAffected":2,"numAtRisk":4,"numEvents":2},{"groupId":"EG002","numAffected":1,"numAtRisk":3,"numEvents":1},{"groupId":"EG003","numAffected":3,"numAtRisk":6,"numEvents":3}],"term":"Platelet count decreased"},{"organSystem":"Investigations","sourceVocabulary":"MedDRA (11.1)","stats":[{"groupId":"EG000","numAffected":0,"numAtRisk":3,"numEvents":0},{"groupId":"EG001","numAffected":0,"numAtRisk":4,"numEvents":0},{"groupId":"EG002","numAffected":1,"numAtRisk":3,"numEvents":1},{"groupId":"EG003","numAffected":1,"numAtRisk":6,"numEvents":1}],"term":"Protein total decreased"},{"organSystem":"Investigations","sourceVocabulary":"MedDRA (11.1)","stats":[{"groupId":"EG000","numAffected":0,"numAtRisk":3,"numEvents":0},{"groupId":"EG001","numAffected":1,"numAtRisk":4,"numEvents":1},{"groupId":"EG002","numAffected":0,"numAtRisk":3,"numEvents":0},{"groupId":"EG003","numAffected":0,"numAtRisk":6,"numEvents":0}],"term":"Weight decreased"},{"organSystem":"Investigations","sourceVocabulary":"MedDRA (11.1)","stats":[{"groupId":"EG000","numAffected":0,"numAtRisk":3,"numEvents":0},{"groupId":"EG001","numAffected":0,"numAtRisk":4,"numEvents":0},{"groupId":"EG002","numAffected":1,"numAtRisk":3,"numEvents":1},{"groupId":"EG003","numAffected":0,"numAtRisk":6,"numEvents":0}],"term":"Weight increased"},{"organSystem":"Investigations","sourceVocabulary":"MedDRA (11.1)","stats":[{"groupId":"EG000","numAffected":1,"numAtRisk":3,"numEvents":1},{"groupId":"EG001","numAffected":2,"numAtRisk":4,"numEvents":2},{"groupId":"EG002","numAffected":3,"numAtRisk":3,"numEvents":3},{"groupId":"EG003","numAffected":4,"numAtRisk":6,"numEvents":4}],"term":"White blood cell count decreased"},{"organSystem":"Investigations","sourceVocabulary":"MedDRA (11.1)","stats":[{"groupId":"EG000","numAffected":0,"numAtRisk":3,"numEvents":0},{"groupId":"EG001","numAffected":1,"numAtRisk":4,"numEvents":1},{"groupId":"EG002","numAffected":0,"numAtRisk":3,"numEvents":0},{"groupId":"EG003","numAffected":0,"numAtRisk":6,"numEvents":0}],"term":"White blood cell count increased"},{"organSystem":"Investigations","sourceVocabulary":"MedDRA (11.1)","stats":[{"groupId":"EG000","numAffected":1,"numAtRisk":3,"numEvents":1},{"groupId":"EG001","numAffected":1,"numAtRisk":4,"numEvents":1},{"groupId":"EG002","numAffected":0,"numAtRisk":3,"numEvents":0},{"groupId":"EG003","numAffected":0,"numAtRisk":6,"numEvents":0}],"term":"Eosinophil percentage increased"},{"organSystem":"Investigations","sourceVocabulary":"MedDRA (11.1)","stats":[{"groupId":"EG000","numAffected":1,"numAtRisk":3,"numEvents":1},{"groupId":"EG001","numAffected":2,"numAtRisk":4,"numEvents":2},{"groupId":"EG002","numAffected":0,"numAtRisk":3,"numEvents":0},{"groupId":"EG003","numAffected":1,"numAtRisk":6,"numEvents":1}],"term":"Blood alkaline phosphatase increased"},{"organSystem":"Investigations","sourceVocabulary":"MedDRA (11.1)","stats":[{"groupId":"EG000","numAffected":0,"numAtRisk":3,"numEvents":0},{"groupId":"EG001","numAffected":1,"numAtRisk":4,"numEvents":1},{"groupId":"EG002","numAffected":0,"numAtRisk":3,"numEvents":0},{"groupId":"EG003","numAffected":0,"numAtRisk":6,"numEvents":0}],"term":"Platelet function test abnormal"},{"organSystem":"Metabolism and nutrition disorders","sourceVocabulary":"MedDRA (11.1)","stats":[{"groupId":"EG000","numAffected":0,"numAtRisk":3,"numEvents":0},{"groupId":"EG001","numAffected":0,"numAtRisk":4,"numEvents":0},{"groupId":"EG002","numAffected":0,"numAtRisk":3,"numEvents":0},{"groupId":"EG003","numAffected":1,"numAtRisk":6,"numEvents":1}],"term":"Anorexia"},{"organSystem":"Metabolism and nutrition disorders","sourceVocabulary":"MedDRA (11.1)","stats":[{"groupId":"EG000","numAffected":1,"numAtRisk":3,"numEvents":1},{"groupId":"EG001","numAffected":1,"numAtRisk":4,"numEvents":1},{"groupId":"EG002","numAffected":0,"numAtRisk":3,"numEvents":0},{"groupId":"EG003","numAffected":1,"numAtRisk":6,"numEvents":1}],"term":"Hypoalbuminaemia"},{"organSystem":"Nervous system disorders","sourceVocabulary":"MedDRA (11.1)","stats":[{"groupId":"EG000","numAffected":0,"numAtRisk":3,"numEvents":0},{"groupId":"EG001","numAffected":1,"numAtRisk":4,"numEvents":1},{"groupId":"EG002","numAffected":0,"numAtRisk":3,"numEvents":0},{"groupId":"EG003","numAffected":0,"numAtRisk":6,"numEvents":0}],"term":"Dizziness"},{"organSystem":"Nervous system disorders","sourceVocabulary":"MedDRA (11.1)","stats":[{"groupId":"EG000","numAffected":0,"numAtRisk":3,"numEvents":0},{"groupId":"EG001","numAffected":1,"numAtRisk":4,"numEvents":1},{"groupId":"EG002","numAffected":0,"numAtRisk":3,"numEvents":0},{"groupId":"EG003","numAffected":0,"numAtRisk":6,"numEvents":0}],"term":"Sensory disturbance"},{"organSystem":"Respiratory, thoracic and mediastinal disorders","sourceVocabulary":"MedDRA (11.1)","stats":[{"groupId":"EG000","numAffected":0,"numAtRisk":3,"numEvents":0},{"groupId":"EG001","numAffected":1,"numAtRisk":4,"numEvents":1},{"groupId":"EG002","numAffected":0,"numAtRisk":3,"numEvents":0},{"groupId":"EG003","numAffected":0,"numAtRisk":6,"numEvents":0}],"term":"Cough"},{"organSystem":"Skin and subcutaneous tissue disorders","sourceVocabulary":"MedDRA (11.1)","stats":[{"groupId":"EG000","numAffected":0,"numAtRisk":3,"numEvents":0},{"groupId":"EG001","numAffected":0,"numAtRisk":4,"numEvents":0},{"groupId":"EG002","numAffected":1,"numAtRisk":3,"numEvents":1},{"groupId":"EG003","numAffected":0,"numAtRisk":6,"numEvents":0}],"term":"Acne"},{"organSystem":"Skin and subcutaneous tissue disorders","sourceVocabulary":"MedDRA (11.1)","stats":[{"groupId":"EG000","numAffected":0,"numAtRisk":3,"numEvents":0},{"groupId":"EG001","numAffected":1,"numAtRisk":4,"numEvents":1},{"groupId":"EG002","numAffected":0,"numAtRisk":3,"numEvents":0},{"groupId":"EG003","numAffected":2,"numAtRisk":6,"numEvents":2}],"term":"Pruritus"},{"organSystem":"Vascular disorders","sourceVocabulary":"MedDRA (11.1)","stats":[{"groupId":"EG000","numAffected":1,"numAtRisk":3,"numEvents":1},{"groupId":"EG001","numAffected":1,"numAtRisk":4,"numEvents":1},{"groupId":"EG002","numAffected":0,"numAtRisk":3,"numEvents":0},{"groupId":"EG003","numAffected":0,"numAtRisk":6,"numEvents":0}],"term":"Hypertension"}],"seriousEvents":[{"organSystem":"Infections and infestations","sourceVocabulary":"MedDRA (11.1)","stats":[{"groupId":"EG000","numAffected":1,"numAtRisk":3,"numEvents":1},{"groupId":"EG001","numAffected":0,"numAtRisk":4,"numEvents":0},{"groupId":"EG002","numAffected":0,"numAtRisk":3,"numEvents":0},{"groupId":"EG003","numAffected":0,"numAtRisk":6,"numEvents":0}],"term":"Herpes zoster"},{"organSystem":"Respiratory, thoracic and mediastinal disorders","sourceVocabulary":"MedDRA (11.1)","stats":[{"groupId":"EG000","numAffected":0,"numAtRisk":3,"numEvents":0},{"groupId":"EG001","numAffected":1,"numAtRisk":4,"numEvents":1},{"groupId":"EG002","numAffected":0,"numAtRisk":3,"numEvents":0},{"groupId":"EG003","numAffected":0,"numAtRisk":6,"numEvents":0}],"term":"Hypoxia"},{"organSystem":"Skin and subcutaneous tissue disorders","sourceVocabulary":"MedDRA (11.1)","stats":[{"groupId":"EG000","numAffected":0,"numAtRisk":3,"numEvents":0},{"groupId":"EG001","numAffected":0,"numAtRisk":4,"numEvents":0},{"groupId":"EG002","numAffected":0,"numAtRisk":3,"numEvents":0},{"groupId":"EG003","numAffected":1,"numAtRisk":6,"numEvents":1}],"term":"Rash"}],"timeFrame":"28 days"}