{"analyses":[{"ciNumSides":"TWO_SIDED","ciPctValue":"95","groupDescription":"The incidences of grade 3 or higher neutropenia, with or without fever between UGT1A1 Genotypes (6/6, 6/7, 7/7) were compared by the Fisher's exact test.","groupIds":["OG000","OG001","OG002"],"nonInferiorityType":"SUPERIORITY_OR_OTHER_LEGACY","pValue":"0.99","statisticalMethod":"Fisher Exact"},{"ciNumSides":"TWO_SIDED","ciPctValue":"95","groupDescription":"The incidences of grade 3 or higher diarrhea between UGT1A1 Genotypes (6/6, 6/7, 7/7) were compared by Fisher's exact test.","groupIds":["OG000","OG001","OG002"],"nonInferiorityType":"SUPERIORITY_OR_OTHER_LEGACY","pValue":"0.036","statisticalMethod":"Fisher Exact"}],"classes":[{"categories":[{"measurements":[{"groupId":"OG000","value":"16"},{"groupId":"OG001","value":"22"},{"groupId":"OG002","value":"4"}]}],"title":"Neutropenia, with or without Fever"},{"categories":[{"measurements":[{"groupId":"OG000","value":"5"},{"groupId":"OG001","value":"14"},{"groupId":"OG002","value":"5"}]}],"title":"Diarrhea"}],"denoms":[{"counts":[{"groupId":"OG000","value":"49"},{"groupId":"OG001","value":"65"},{"groupId":"OG002","value":"12"}],"units":"Participants"}],"description":"Severe and undesirable adverse event is considered as grade 3; Life-threatening or disabling adverse event is grade 4. Grade 4 is worse than grade 3.","groups":[{"id":"OG000","title":"UGT1A1 Genotype 6/6"},{"id":"OG001","title":"UGT1A1 Genotype 6/7"},{"id":"OG002","title":"UGT1A1 Genotype 7/7"}],"paramType":"NUMBER","populationDescription":"Ineligible patients are excluded. Only patients tested for the UGT1A1 genotypes are reported and included in this analysis.","reportingStatus":"POSTED","timeFrame":"Weeks 4-9 (the first exposure to VI)","title":"Incidence of Toxicity Related to VI Treatment in Patients With UGT1A1 Genotype","type":"SECONDARY","unitOfMeasure":"Counts"}