{"anticipatedPostingDate":"2009-11","classes":[{"categories":[{"measurements":[{"groupId":"OG000","value":"6"}]}]}],"denoms":[{"counts":[{"groupId":"OG000","value":"15"}],"units":"Participants"}],"description":"Graft-versus-host disease (GVHD) is a common complication of transplantation in which functional immune cells in the transplanted marrow recognize the recipient as foreign and mount an immunologic attack. The acute or fulminant form of the disease (aGVHD) is normally observed within the first 100 days post-transplant, and is a major challenge to transplants owing to associated morbidity and mortality. Acute GVHD is staged as follows: overall grade (skin-liver-gut) with each organ staged individually from a low of I to a high of IV. Patients with grade IV GVHD usually have a poor prognosis.","groups":[{"description":"All patients receiving full study treatment with chemotherapy and radiation, along with natural killer cells, aldesleukin and umbilical cord blood transplant.","id":"OG000","title":"Evaluable Patients"}],"paramType":"NUMBER","reportingStatus":"POSTED","timeFrame":"Day 100 Post Transplant","title":"Number of Participants (Patients) With Acute Graft-versus-host Disease (GVHD) Grade II-IV","type":"SECONDARY","unitOfMeasure":"Participants"}