{"analyses":[{"ciLowerLimit":"0.36","ciNumSides":"TWO_SIDED","ciPctValue":"95","ciUpperLimit":"0.48","groupDescription":"Kappa statistic and its 95% confidence interval are used to assess agreement beyond random.","groupIds":["OG000","OG001","OG002"],"nonInferiorityType":"OTHER","paramType":"Kappa statistic","paramValue":"0.42"}],"classes":[{"categories":[{"measurements":[{"groupId":"OG000","value":"46"},{"groupId":"OG001","value":"8"},{"groupId":"OG002","value":"1"}]}],"title":"Histologic grade 1 by POG"},{"categories":[{"measurements":[{"groupId":"OG000","value":"24"},{"groupId":"OG001","value":"69"},{"groupId":"OG002","value":"0"}]}],"title":"Histologic grade 2 by POG"},{"categories":[{"measurements":[{"groupId":"OG000","value":"9"},{"groupId":"OG001","value":"145"},{"groupId":"OG002","value":"240"}]}],"title":"Histologic grade 3 by POG"}],"denoms":[{"counts":[{"groupId":"OG000","value":"79"},{"groupId":"OG001","value":"222"},{"groupId":"OG002","value":"241"}],"units":"Participants"}],"description":"POG and FNCLCC grades were determined by pathologists based on published standards. A higher grade is associated with a more severe disease.","groups":[{"id":"OG000","title":"Histologic Grade 1 by FNCLCC"},{"id":"OG001","title":"Histologic Grade 2 by FNCLCC"},{"id":"OG002","title":"Histologic Grade 3 by FNCLCC"}],"paramType":"COUNT_OF_PARTICIPANTS","populationDescription":"Ineligible patients, as well as patients without histologic grade determined by POG or FNCLCC were excluded. The OM evaluates the degree of agreement of two pathology grading systems applied at diagnosis. The time frame \"At diagnosis\" reflects the OM.","reportingStatus":"POSTED","timeFrame":"At diagnosis","title":"Degree of Agreement in Histologic Grade Between Pediatric Oncology Group (POG) and Fédération Nationale Des Centres de Lutte Contre le Cancer (FNCLCC) Pathologic Grading Systems","type":"SECONDARY","unitOfMeasure":"Participants"}