{"classes":[{"categories":[{"measurements":[{"groupId":"OG000","value":"0"}]}],"title":"C229R mutation in p53 in Patients from Brazil"},{"categories":[{"measurements":[{"groupId":"OG000","value":"2"}]}],"title":"C229R mutation in Patients not from Brazil"},{"categories":[{"measurements":[{"groupId":"OG000","value":"0"}]}],"title":"E180K mutation in p53 in Patients from Brazil"},{"categories":[{"measurements":[{"groupId":"OG000","value":"1"}]}],"title":"E180K mutation in Patients not from Brazil"},{"categories":[{"measurements":[{"groupId":"OG000","value":"0"}]}],"title":"G245C mutation in p53 in Patients from Brazil"},{"categories":[{"measurements":[{"groupId":"OG000","value":"1"}]}],"title":"G245C mutation in Patients not from Brazil"},{"categories":[{"measurements":[{"groupId":"OG000","value":"1"}]}],"title":"I254T mutation in p53 in Patients from Brazil"},{"categories":[{"measurements":[{"groupId":"OG000","value":"0"}]}],"title":"I254T mutation in Patients not from Brazil"},{"categories":[{"measurements":[{"groupId":"OG000","value":"0"}]}],"title":"L265Q mutation in p53 in Patients from Brazil"},{"categories":[{"measurements":[{"groupId":"OG000","value":"1"}]}],"title":"L265Q mutation in Patients not from Brazil"},{"categories":[{"measurements":[{"groupId":"OG000","value":"0"}]}],"title":"P47S mutation in p53 in Patients from Brazil"},{"categories":[{"measurements":[{"groupId":"OG000","value":"1"}]}],"title":"P47S mutation in Patients not from Brazil"},{"categories":[{"measurements":[{"groupId":"OG000","value":"0"}]}],"title":"Q52fs mutation in p53 in Patients from Brazil"},{"categories":[{"measurements":[{"groupId":"OG000","value":"1"}]}],"title":"Q52fs mutation in Patients not from Brazil"},{"categories":[{"measurements":[{"groupId":"OG000","value":"0"}]}],"title":"R158L mutation in Patients from Brazil"},{"categories":[{"measurements":[{"groupId":"OG000","value":"1"}]}],"title":"R158L mutation in Patients not from Brazil"},{"categories":[{"measurements":[{"groupId":"OG000","value":"0"}]}],"title":"G245S mutation in Patients from Brazil"},{"categories":[{"measurements":[{"groupId":"OG000","value":"1"}]}],"title":"G245S mutation in Patients not from Brazil"},{"categories":[{"measurements":[{"groupId":"OG000","value":"0"}]}],"title":"R213P mutation in p53 in Patients from Brazil"},{"categories":[{"measurements":[{"groupId":"OG000","value":"1"}]}],"title":"R213P mutation in Patients not from Brazil"},{"categories":[{"measurements":[{"groupId":"OG000","value":"0"}]}],"title":"R248L mutation in Patients from Brazil"},{"categories":[{"measurements":[{"groupId":"OG000","value":"1"}]}],"title":"R248L mutation in Patients not from Brazil"},{"categories":[{"measurements":[{"groupId":"OG000","value":"0"}]}],"title":"R282W mutation in p53 in Patients from Brazil"},{"categories":[{"measurements":[{"groupId":"OG000","value":"1"}]}],"title":"R282W mutation in p53 in Patients not from Brazil"},{"categories":[{"measurements":[{"groupId":"OG000","value":"0"}]}],"title":"R283H mutation in p53 in Patients from Brazil"},{"categories":[{"measurements":[{"groupId":"OG000","value":"31"}]}],"title":"R283H mutation in p53 in Patients not from Brazil"},{"categories":[{"measurements":[{"groupId":"OG000","value":"20"}]}],"title":"R337H mutation in p53 in Patients from Brazil"},{"categories":[{"measurements":[{"groupId":"OG000","value":"0"}]}],"title":"R337H mutation in p53 in Patients not from Brazil"},{"categories":[{"measurements":[{"groupId":"OG000","value":"0"}]}],"title":"R342X mutation in p53 in Patients from Brazil"},{"categories":[{"measurements":[{"groupId":"OG000","value":"1"}]}],"title":"R342X mutation in p53 in Patients not from Brazil"},{"categories":[{"measurements":[{"groupId":"OG000","value":"1"}]}],"title":"T125T c375G>A muation in p53 in Pts from Brazil"},{"categories":[{"measurements":[{"groupId":"OG000","value":"1"}]}],"title":"T125T c375G>A mutation in p53 in pts not from Braz"},{"categories":[{"measurements":[{"groupId":"OG000","value":"0"}]}],"title":"T125T splice in DBD in pts from Brazil"},{"categories":[{"measurements":[{"groupId":"OG000","value":"1"}]}],"title":"T125T splice in DBD in pts not from Brazil"},{"categories":[{"measurements":[{"groupId":"OG000","value":"1"}]}],"title":"wild type p53 in Patients from Brazil"},{"categories":[{"measurements":[{"groupId":"OG000","value":"16"}]}],"title":"wild type p53 in Patients not from Brazil"}],"denoms":[{"counts":[{"groupId":"OG000","value":"54"}],"units":"Participants"}],"description":"The proportion of patients in each subpopulation are compared.This test is dependent on the number of patients from whom blood can be obtained as well as the frequency of the relevant mutation in each group.","groups":[{"description":"Regardless of Arm/Group assignment, the number of eligible patients from whom blood was obtained as well as the frequency of the relevant mutation in each group.","id":"OG000","title":"All Patients"}],"paramType":"NUMBER","populationDescription":"The proportion of patients in each subpopulation are compared.This test is dependent on the number of patients from whom blood can be obtained as well as the frequency of the relevant mutation in each group (Number of patients from Brazil: 23. Number of patients not from Brazil: 31)","reportingStatus":"POSTED","timeFrame":"At study enrollment","title":"Incidence and Type of Germline TP53 Mutations in Non-Brazilian Children and Children From Southern Brazil by Deoxyribonucleic Acid (DNA) Sequencing and Affymetrix Gene Chip Analysis.","type":"SECONDARY","unitOfMeasure":"participants"}