{"groups":[{"description":"Participants with surgically staged carcinosarcoma (CS) with no gross residual disease were initially administered ifosfamide (1.2 g/m2/day for 5 days) with cisplatin (20 mg/m2/day for 5 days) every 3 weeks for 3 cycles followed by pelvic external beam RT and brachytherapy followed by 3 additional cycles of ifosfamide (1.0 g/m2/day) with cisplatin with cisplatin (20 mg/m2/day for 5 days) evrey 3 weeks. cisplatin added toxicity without additional efficacy, so mid-study, cisplatin was eliminated.","id":"FG000","title":"Chemotherapy and Radiation Therapy"}],"periods":[{"dropWithdraws":[{"reasons":[{"groupId":"FG000","numSubjects":"3"}],"type":"Withdrawal by Subject"},{"reasons":[{"groupId":"FG000","numSubjects":"8"}],"type":"Did not complete the last 3 cycle"}],"milestones":[{"achievements":[{"groupId":"FG000","numSubjects":"30"}],"type":"STARTED"},{"achievements":[{"groupId":"FG000","numSubjects":"27"}],"type":"Initiated Therapy"},{"achievements":[{"groupId":"FG000","numSubjects":"27"}],"comment":"27 participants completed the first 3 cycles of chemotherapy followed by RT","type":"Completed First 3 Cycles"},{"achievements":[{"groupId":"FG000","numSubjects":"27"}],"comment":"26 participants had EBRT + Brachytherapy; 1 had EBRT alone","type":"Completed Prescribed RT"},{"achievements":[{"groupId":"FG000","numSubjects":"19"}],"type":"Completed Full Prescribed Therapy"},{"achievements":[{"groupId":"FG000","numSubjects":"19"}],"type":"COMPLETED"},{"achievements":[{"groupId":"FG000","numSubjects":"11"}],"type":"NOT COMPLETED"}],"title":"Overall Study"}],"preAssignmentDetails":"30 participants were enrolled and 3 participants withdrew prior to therapy. Twenty-seven participants received the first three cycles of chemotherapy and Radiation Therapy and were included in the analysis.","recruitmentDetails":"Eligible participants with surgically staged I-IV uterine carcinosarcoma (CS) without evidence of gross residual disease after primary surgery were recruited from 1999 to 2009 . Eligible participants underwent surgical staging when clinically indicated."}