{"analyses":[{"groupIds":["OG000"],"nonInferiorityType":"SUPERIORITY_OR_OTHER_LEGACY","pValue":"0.0000007","statisticalMethod":"Wilcoxon (Mann-Whitney)"}],"classes":[{"categories":[{"measurements":[{"groupId":"OG000","lowerLimit":"31.4","upperLimit":"58.7","value":"41.2"}]}],"title":"Prednisolone-sensitive cells"},{"categories":[{"measurements":[{"groupId":"OG000","lowerLimit":"59.7","upperLimit":"157.6","value":"110.7"}]}],"title":"Prednisolone-resistant cells"}],"denoms":[{"counts":[{"groupId":"OG000","value":"144"}],"units":"Participants"}],"description":"Prednisolone sensitivity was measured in primary leukemia cells from bone marrow collected at diagnosis. Expression of NLRP3 was determined by HG-U133A microarray. Values given are gene expression values, and the unit is arbitrary units (AU) defined as scaled fluorescence measured on microarray.","dispersionType":"Inter-Quartile Range","groups":[{"description":"Total therapy applies to all eligible patients.","id":"OG000","title":"Total Therapy"}],"paramType":"MEDIAN","populationDescription":"One hundred forty-four (144) patients were evaluable to assess prednisolone sensitivity measured in bone marrow ALL cells and NLRP3 expression in RNA by MTT assay","reportingStatus":"POSTED","timeFrame":"Pre-treatment","title":"Median Difference in NLRP3 Gene Expression in Primary Leukemia Cells of Patients in Glucocorticoid-resistant Cells vs. Glucocorticoid-sensitive Cells","type":"OTHER_PRE_SPECIFIED","unitOfMeasure":"arbitrary units"}