{"analyses":[{"groupIds":["OG000"],"nonInferiorityType":"SUPERIORITY_OR_OTHER_LEGACY","pValue":"0.00000095","statisticalMethod":"Wilcoxon (Mann-Whitney)"}],"classes":[{"categories":[{"measurements":[{"groupId":"OG000","lowerLimit":"202.1","upperLimit":"430.2","value":"341.3"}]}],"title":"Prednisolone-sensitive cells"},{"categories":[{"measurements":[{"groupId":"OG000","lowerLimit":"332.2","upperLimit":"544.9","value":"447.9"}]}],"title":"Prednisolone-resistant cells"}],"denoms":[{"counts":[{"groupId":"OG000","value":"144"}],"units":"Participants"}],"description":"Prednisolone sensitivity was measured in primary leukemia cells from bone marrow collected at diagnosis. Expression of CASP1 was determined by HG-U133A microarray. Values given are gene expression values, and the unit is arbitrary units (AU) defined as scaled fluorescence measured on microarray.","dispersionType":"Inter-Quartile Range","groups":[{"description":"Total therapy applies to all eligible patients.","id":"OG000","title":"Total Therapy"}],"paramType":"MEDIAN","populationDescription":"One hundred forty-four (144) patients were evaluable to assess prednisolone sensitivity measured in bone marrow ALL cells and CASP1 expression in RNA by MTT assay.","reportingStatus":"POSTED","timeFrame":"Pre-treatment","title":"Median Difference in CASP1 Gene Expression in Primary Leukemia Cells of Patients in Glucocorticoid-resistant Cells vs Glucocorticoid-sensitive Cells","type":"OTHER_PRE_SPECIFIED","unitOfMeasure":"arbitrary units"}