{"groups":[{"description":"Patients receive fludarabine phosphate IV over 30 minutes on days -4, -3, and -2. Patients also undergo low-dose TBI on day 0.\n\nTotal-body irradiation: Undergo low-dose total-body irradiation\n\nFludarabine phosphate: Given IV\n\nAllogeneic hematopoietic stem cell transplantation: Undergo allogeneic stem cell transplantation\n\nPeripheral blood stem cell transplantation: Undergo peripheral blood stem cell transplantation","id":"FG000","title":"Dose Level 1 (No Campath)"},{"description":"Patients receive alemtuzumab IV over 6 hours once daily on days -5 and -4 and fludarabine phosphate IV over 30 minutes on days -4, -3, and -2. Patients also undergo low-dose TBI on day 0.\n\nAlemtuzumab: Given IV\n\nTotal-body irradiation: Undergo low-dose total-body irradiation\n\nFludarabine phosphate: Given IV\n\nAllogeneic hematopoietic stem cell transplantation: Undergo allogeneic stem cell transplantation\n\nPeripheral blood stem cell transplantation: Undergo peripheral blood stem cell transplantation\n\nNOTE: No subjects were enrolled at this dose level as the escalation rule was not met.","id":"FG001","title":"Dose Level 2 (40mg Total Dose Campath)"},{"description":"Patients receive alemtuzumab IV over 6 hours once daily on days -6, -5, and -4 and fludarabine phosphate IV over 30 minutes on days -4, -3, and -2. Patients also undergo low-dose TBI on day 0.\n\nAlemtuzumab: Given IV\n\nTotal-body irradiation: Undergo low-dose total-body irradiation\n\nFludarabine phosphate: Given IV\n\nAllogeneic hematopoietic stem cell transplantation: Undergo allogeneic stem cell transplantation\n\nPeripheral blood stem cell transplantation: Undergo peripheral blood stem cell transplantation\n\nNOTE: No subjects were enrolled at this dose level as the escalation rule was not met.","id":"FG002","title":"Dose Level 3 (60mg Total Dose Campath)"}],"periods":[{"milestones":[{"achievements":[{"groupId":"FG000","numSubjects":"12"},{"groupId":"FG001","numSubjects":"0"},{"groupId":"FG002","numSubjects":"0"}],"type":"STARTED"},{"achievements":[{"groupId":"FG000","numSubjects":"12"},{"groupId":"FG001","numSubjects":"0"},{"groupId":"FG002","numSubjects":"0"}],"type":"COMPLETED"},{"achievements":[{"groupId":"FG000","numSubjects":"0"},{"groupId":"FG001","numSubjects":"0"},{"groupId":"FG002","numSubjects":"0"}],"type":"NOT COMPLETED"}],"title":"Overall Study"}]}