{"classes":[{"categories":[{"measurements":[{"groupId":"OG000","value":"0"}]}]}],"denoms":[{"counts":[{"groupId":"OG000","value":"12"},{"groupId":"OG001","value":"0"},{"groupId":"OG002","value":"0"}],"units":"Participants"}],"description":"Percentage patients that experienced graft rejection.","groups":[{"description":"Patients receive fludarabine phosphate IV over 30 minutes on days -4, -3, and -2. Patients also undergo low-dose TBI on day 0.\n\nTotal-body irradiation: Undergo low-dose total-body irradiation\n\nFludarabine phosphate: Given IV\n\nAllogeneic hematopoietic stem cell transplantation: Undergo allogeneic stem cell transplantation\n\nPeripheral blood stem cell transplantation: Undergo peripheral blood stem cell transplantation","id":"OG000","title":"Dose Level 1 (No Campath)"},{"description":"Patients receive alemtuzumab IV over 6 hours once daily on days -5 and -4 and fludarabine phosphate IV over 30 minutes on days -4, -3, and -2. Patients also undergo low-dose TBI on day 0.\n\nAlemtuzumab: Given IV\n\nTotal-body irradiation: Undergo low-dose total-body irradiation\n\nFludarabine phosphate: Given IV\n\nAllogeneic hematopoietic stem cell transplantation: Undergo allogeneic stem cell transplantation\n\nPeripheral blood stem cell transplantation: Undergo peripheral blood stem cell transplantation","id":"OG001","title":"Dose Level 2 (40mg Total Dose Campath)"},{"description":"Patients receive alemtuzumab IV over 6 hours once daily on days -6, -5, and -4 and fludarabine phosphate IV over 30 minutes on days -4, -3, and -2. Patients also undergo low-dose TBI on day 0.\n\nAlemtuzumab: Given IV\n\nTotal-body irradiation: Undergo low-dose total-body irradiation\n\nFludarabine phosphate: Given IV\n\nAllogeneic hematopoietic stem cell transplantation: Undergo allogeneic stem cell transplantation\n\nPeripheral blood stem cell transplantation: Undergo peripheral blood stem cell transplantation","id":"OG002","title":"Dose Level 3 (60mg Total Dose Campath)"}],"paramType":"NUMBER","reportingStatus":"POSTED","timeFrame":"84 days after transplant","title":"Incidence of Graft Rejection","type":"SECONDARY","unitOfMeasure":"percentage of participants"}