{"groups":[{"description":"See Detailed Description\n\ntotal marrow irradiation: Undergo irradiation escalating according to the following schedule 1000cGy, 1200cGy, 1400cGy, 1600cGy, 1800cGy\n\nmelphalan: Given IV\n\nperipheral blood stem cell transplantation: Undergo transplantation\n\nfilgrastim: Given IV\n\nfluorescence in situ hybridization: Correlative studies\n\ncytogenetic analysis: Correlative studies\n\ncyclophosphamide: Given IV\n\nautologous-autologous tandem hematopoietic stem cell transplantation: Undergo transplantation\n\nlenalidomide: Given orally","id":"FG000","title":"Phase 1 Cohort 1 (Total TMI Dose: 1000 cGy)"},{"description":"See Detailed Description\n\ntotal marrow irradiation: Undergo irradiation escalating according to the following schedule 1000cGy, 1200cGy, 1400cGy, 1600cGy, 1800cGy\n\nmelphalan: Given IV\n\nperipheral blood stem cell transplantation: Undergo transplantation\n\nfilgrastim: Given IV\n\nfluorescence in situ hybridization: Correlative studies\n\ncytogenetic analysis: Correlative studies\n\ncyclophosphamide: Given IV\n\nautologous-autologous tandem hematopoietic stem cell transplantation: Undergo transplantation\n\nlenalidomide: Given orally","id":"FG001","title":"Phase 1 Cohort 2 (Total TMI Dose: 1200 cGy)"},{"description":"See Detailed Description\n\ntotal marrow irradiation: Undergo irradiation escalating according to the following schedule 1000cGy, 1200cGy, 1400cGy, 1600cGy, 1800cGy\n\nmelphalan: Given IV\n\nperipheral blood stem cell transplantation: Undergo transplantation\n\nfilgrastim: Given IV\n\nfluorescence in situ hybridization: Correlative studies\n\ncytogenetic analysis: Correlative studies\n\ncyclophosphamide: Given IV\n\nautologous-autologous tandem hematopoietic stem cell transplantation: Undergo transplantation\n\nlenalidomide: Given orally","id":"FG002","title":"Phase 1 Cohort 3 (Total TMI Dose: 1400 cGy)"},{"description":"See Detailed Description\n\ntotal marrow irradiation: Undergo irradiation escalating according to the following schedule 1000cGy, 1200cGy, 1400cGy, 1600cGy, 1800cGy\n\nmelphalan: Given IV\n\nperipheral blood stem cell transplantation: Undergo transplantation\n\nfilgrastim: Given IV\n\nfluorescence in situ hybridization: Correlative studies\n\ncytogenetic analysis: Correlative studies\n\ncyclophosphamide: Given IV\n\nautologous-autologous tandem hematopoietic stem cell transplantation: Undergo transplantation\n\nlenalidomide: Given orally","id":"FG003","title":"Phase 1 Cohort 4 & Phase 2 MTD (Total TMI Dose:1600 cGy)"},{"description":"See Detailed Description\n\ntotal marrow irradiation: Undergo irradiation escalating according to the following schedule 1000cGy, 1200cGy, 1400cGy, 1600cGy, 1800cGy\n\nmelphalan: Given IV\n\nperipheral blood stem cell transplantation: Undergo transplantation\n\nfilgrastim: Given IV\n\nfluorescence in situ hybridization: Correlative studies\n\ncytogenetic analysis: Correlative studies\n\ncyclophosphamide: Given IV\n\nautologous-autologous tandem hematopoietic stem cell transplantation: Undergo transplantation\n\nlenalidomide: Given orally","id":"FG004","title":"Phase 1 Cohort 5 (Total TMI Dose: 1800 cGy)"}],"periods":[{"milestones":[{"achievements":[{"groupId":"FG000","numSubjects":"3"},{"groupId":"FG001","numSubjects":"4"},{"groupId":"FG002","numSubjects":"4"},{"groupId":"FG003","numSubjects":"36"},{"groupId":"FG004","numSubjects":"7"}],"type":"STARTED"},{"achievements":[{"groupId":"FG000","numSubjects":"3"},{"groupId":"FG001","numSubjects":"4"},{"groupId":"FG002","numSubjects":"4"},{"groupId":"FG003","numSubjects":"36"},{"groupId":"FG004","numSubjects":"7"}],"type":"COMPLETED"},{"achievements":[{"groupId":"FG000","numSubjects":"0"},{"groupId":"FG001","numSubjects":"0"},{"groupId":"FG002","numSubjects":"0"},{"groupId":"FG003","numSubjects":"0"},{"groupId":"FG004","numSubjects":"0"}],"type":"NOT COMPLETED"}],"title":"Overall Study"}]}