{"groups":[{"description":"Patients receive tacrolimus IV or PO every 12 hours on days -3 to 180 with taper beginning on day 100 in the absence of GVHD. Patients also receive Mycophenolate Mofetil \\[MMF\\] PO every 8 hours on days 0-29 and then every 12 hours on days 30-96 with taper beginning on day 40 in the absence of GVHD.\n\nFludarabine Phosphate: Given IV\n\nTotal-Body Irradiation: Undergo total-body irradiation\n\nPeripheral Blood Stem Cell Transplantation: Undergo allogeneic peripheral blood stem cell transplantation\n\nAllogeneic Hematopoietic Stem Cell Transplantation: Undergo allogeneic peripheral blood stem cell transplantation\n\nTacrolimus: Given IV or PO\n\nMycophenolate Mofetil: Given PO","id":"FG000","title":"Arm I (MMF and Tacrolimus)"},{"description":"Patients receive tacrolimus IV or PO every 12 hours on days -3 to 150 with taper beginning on day 100 in the absence of GVHD. Patients also receive Mycophenolate Mofetil \\[MMF\\] PO every 8 hours on days 0-29 and then every 12 hours on days 30-180 with taper beginning on day 150 in the absence of GVHD.\n\nFludarabine Phosphate: Given IV\n\nTotal-Body Irradiation: Undergo total-body irradiation\n\nPeripheral Blood Stem Cell Transplantation: Undergo allogeneic peripheral blood stem cell transplantation\n\nAllogeneic Hematopoietic Stem Cell Transplantation: Undergo allogeneic peripheral blood stem cell transplantation\n\nTacrolimus: Given IV or PO\n\nMycophenolate Mofetil: Given PO","id":"FG001","title":"Arm II (MMF and Tacrolimus Alternate Schedule)"},{"description":"Patients receive tacrolimus and Mycophenolate Mofetil \\[MMF\\] as in arm II. Patients also receive sirolimus PO once daily on days -3 to 80.\n\nFludarabine Phosphate: Given IV\n\nTotal-Body Irradiation: Undergo total-body irradiation\n\nPeripheral Blood Stem Cell Transplantation: Undergo allogeneic peripheral blood stem cell transplantation\n\nAllogeneic Hematopoietic Stem Cell Transplantation: Undergo allogeneic peripheral blood stem cell transplantation\n\nTacrolimus: Given IV or PO\n\nMycophenolate Mofetil: Given PO\n\nSirolimus: Given PO","id":"FG002","title":"Arm III (MMF, Tacrolimus, and Sirolimus)"}],"periods":[{"milestones":[{"achievements":[{"groupId":"FG000","numSubjects":"70"},{"groupId":"FG001","numSubjects":"71"},{"groupId":"FG002","numSubjects":"69"}],"type":"STARTED"},{"achievements":[{"groupId":"FG000","numSubjects":"70"},{"groupId":"FG001","numSubjects":"71"},{"groupId":"FG002","numSubjects":"69"}],"type":"COMPLETED"},{"achievements":[{"groupId":"FG000","numSubjects":"0"},{"groupId":"FG001","numSubjects":"0"},{"groupId":"FG002","numSubjects":"0"}],"type":"NOT COMPLETED"}],"title":"Overall Study"}]}