{"classes":[{"categories":[{"measurements":[{"groupId":"OG000","lowerLimit":"85.55","upperLimit":"85.61","value":"85.58"}]}]}],"denoms":[{"counts":[{"groupId":"OG000","value":"636"}],"units":"Participants"}],"description":"Event Free Probability where EFS time is defined as time from randomization to first event (relapse, second malignant neoplasm, death) or date of last contact for patients who are event-free.","dispersionType":"95% Confidence Interval","groups":[{"description":"Patients receive intensified consolidation therapy (cyclophosphamide, cytarabine, mercaptopurine and vincristine sulfate, pegaspargase, methotrexate. Patients with DS receive oral leucovorin calcium), augmented interim maintenance therapy (2 courses - vincristine sulfate, MTX and pegaspargase. Patients with DS receive leucovorin calcium, and augmented DI therapy (2 courses - vincristine sulfate, dexamethasone, doxorubicin hydrochloride, pegaspargase, cyclophosphamide, cytarabine, thioguanine,MTX. Patients with DS receive (dexamethasone and leucovorin calcium), followed by maintenance therapy. Therapies are given by mouth, injection, and infusion for up to 2 or 3 years.\n\ndoxorubicin hydrochloride: Given IV or IT\n\n3-dimensional conformal radiation therapy: Some patients undergo cranial radiotherapy\n\ncytarabine: Given IV or SC\n\ndexamethasone: Given IV or PO\n\npegaspargase: Given IM\n\nmethotrexate: Given IM or IT\n\nleucovorin calcium: Given PO\n\nmercaptopurine: Given PO","id":"OG000","title":"Group 3-SR-high ALL, Combination Chemotherapy"}],"paramType":"NUMBER","populationDescription":"CCR: Complete Continuous Remission, where time to event is defined as the time from start of consolidation therapy to first event or date of last follow up for those who did not experience an event. All patients enrolled on the SR-High were used in this analysis regardless of completion of therapy.","reportingStatus":"POSTED","timeFrame":"6 years","title":"Event-free Survival (EFS) for SR-High Patients.","type":"SECONDARY","unitOfMeasure":"percent probability"}