{"classes":[{"categories":[{"measurements":[{"groupId":"OG000","lowerLimit":"60","upperLimit":"82","value":"73"},{"groupId":"OG001","lowerLimit":"66","upperLimit":"86","value":"78"}]}]}],"denoms":[{"counts":[{"groupId":"OG000","value":"70"},{"groupId":"OG001","value":"75"}],"units":"Participants"}],"description":"To compare the 3-year survival achieved by docetaxel/cisplatin/5-FU based sequential therapy with platinum based chemo radiotherapy in patients with locally advanced SCCHN. Overall survival is defined as the time from date of randomisation to death from any cause. Patients alive at the time of current analysis were censored at the date last known to be alive.Kaplan-Meier method was used to estimate overall survival","dispersionType":"95% Confidence Interval","groups":[{"description":"Patients receive induction chemotherapy comprising docetaxel, cisplatin, and fluorouracil. Treatment repeats every 21 days for 3 courses. Patients achieving a pathologic complete response at the primary site and a clinical complete response in the neck then receive carboplatin once weekly and undergo concurrent radiotherapy once daily, 5 days a week, for 7 weeks. Patients with a partial response at the primary site (i.e., positive biopsy), stable disease, or radiographic evidence of persistent disease in the neck receive docetaxel once weekly for 4 weeks and undergo concurrent radiotherapy once or twice daily, 5 days a week, for 6 weeks.\n\ncisplatin : Given IV\n\nradiation therapy : Patients undergo radiation therapy once or twice daily, 5 days a week, for up to 7 weeks\n\ncarboplatin : Given IV\n\nfluorouracil : Given IV\n\ndocetaxel : Given IV","id":"OG000","title":"Arm I"},{"description":"Patients receive cisplatin IV on weeks 1 and 4 and undergo concurrent radiotherapy once or twice daily, 5 days a week, for 6 weeks.\n\ncisplatin : Given IV\n\nradiation therapy : Patients undergo radiation therapy once or twice daily, 5 days a week, for up to 7 weeks","id":"OG001","title":"Arm II"}],"paramType":"NUMBER","reportingStatus":"POSTED","timeFrame":"3-years","title":"Overall Survival","type":"PRIMARY","unitOfMeasure":"percent of patients"}