{"classes":[{"categories":[{"measurements":[{"groupId":"OG000","lowerLimit":"0.046","upperLimit":"0.116","value":"0.081"},{"groupId":"OG001","lowerLimit":"0.035","upperLimit":"0.195","value":"0.115"}]}]}],"denoms":[{"counts":[{"groupId":"OG000","value":"52"},{"groupId":"OG001","value":"62"}],"units":"Participants"}],"description":"The local failure rate will be estimated using cumulative incidence curves.","dispersionType":"95% Confidence Interval","groups":[{"description":"Stage I/II group IIA patients receive VAC chemotherapy comprising vincristine sulfate IV over 1 minute on day 1 of weeks 1-9 and dactinomycin IV over 1 minute and cyclophosphamide IV over 1 hour on day 1 of weeks 1, 4, 7, and 10; VA chemotherapy comprising vincristine sulfate IV over 1 minute on day 1 of weeks 13-21 and dactinomycin IV over 1 minute on day 1 of weeks 13, 16, 19, and 22 (dactinomycin is omitted during radiation therapy); and radiation therapy, 5 days a week, beginning on week 13 and continuing for 4-7 weeks, depending on prescribed dose. Some patients do not receive radiation therapy; some start it at week 24. (closed to accrual as of 08/13/2010)\n\ndactinomycin: Given IV\n\ncyclophosphamide: Given IV\n\nvincristine sulfate: Given IV\n\nradiation therapy: Undergo radiotherapy","id":"OG000","title":"Regimen I (Chemotherapy, Radiotherapy)"},{"description":"Group III patients with orbit primary receive VAC chemotherapy comprising vincristine sulfate IV over 1 minute on day 1 of weeks 1-9 and dactinomycin IV over 1 minute and cyclophosphamide IV over 1 hour on day 1 of weeks 1, 4, 7, and 10; VA chemotherapy comprising vincristine sulfate IV over 1 minute on day 1 of weeks 13-21 and dactinomycin IV over 1 minute on day 1 of weeks 13, 16, 19, and 22 (dactinomycin is omitted during radiation therapy); and radiation therapy, 5 days a week, beginning on week 13 and continuing for 4-7 weeks, depending on prescribed dose. Some patients do not receive radiation therapy; some start it at week 24. (closed to accrual as of 08/13/2010)\n\ndactinomycin: Given IV\n\ncyclophosphamide: Given IV\n\nvincristine sulfate: Given IV\n\nradiation therapy: Undergo radiotherapy","id":"OG001","title":"Regimen II (Chemotherapy, Radiotherapy, Surgery)"}],"paramType":"NUMBER","populationDescription":"Patients who received reduced doses of radiation therapy.","reportingStatus":"POSTED","timeFrame":"From enrollment up to 5 years","title":"Cumulative Incidence of Patients Who Receive Reduced Doses of Radiation Therapy","type":"SECONDARY","unitOfMeasure":"stimated percentage of participants"}