{"eventGroups":[{"description":"RADIOIMMUNOTHERAPY: Patients receive a test dose of iodine I 131 tositumomab IV on day -24 to determine biodistribution. Patients then receive therapeutic iodine I 131 tositumomab IV over approximately 40-60 minutes on day -14 and are entered into radiation isolation until day -4.\n\nCHEMOTHERAPY: Patients receive etoposide IV on day -4 and cyclophosphamide IV on day -2.\n\nAUTOLOGOUS STEM CELL TRANSPLANTATION: Patients undergo autologous peripheral blood stem cell transplantation on day 0.\n\ncyclophosphamide: Given IV\n\netoposide: Given IV\n\niodine I 131 tositumomab: Given IV\n\nquality-of-life assessment: Ancillary study\n\nperipheral blood stem cell transplantation: Undergo ASCT given via central catheter","id":"EG000","otherNumAffected":0,"otherNumAtRisk":107,"seriousNumAffected":9,"seriousNumAtRisk":107,"title":"Treatment (Radio Labeled Monoclonal Antibody, Chemotherapy)"}],"frequencyThreshold":"5","seriousEvents":[{"assessmentType":"SYSTEMATIC_ASSESSMENT","organSystem":"Gastrointestinal disorders","stats":[{"groupId":"EG000","numAffected":2,"numAtRisk":107,"numEvents":2}],"term":"Mucositis/stomatitis"},{"assessmentType":"SYSTEMATIC_ASSESSMENT","organSystem":"Renal and urinary disorders","stats":[{"groupId":"EG000","numAffected":1,"numAtRisk":107,"numEvents":1}],"term":"Renal Failure"},{"organSystem":"Respiratory, thoracic and mediastinal disorders","stats":[{"groupId":"EG000","numAffected":1,"numAtRisk":107,"numEvents":1}],"term":"Respiratory distress"},{"assessmentType":"SYSTEMATIC_ASSESSMENT","organSystem":"Respiratory, thoracic and mediastinal disorders","stats":[{"groupId":"EG000","numAffected":1,"numAtRisk":107,"numEvents":1}],"term":"Idiopathic pneumonia syndrome"},{"assessmentType":"SYSTEMATIC_ASSESSMENT","organSystem":"Respiratory, thoracic and mediastinal disorders","stats":[{"groupId":"EG000","numAffected":1,"numAtRisk":107,"numEvents":1}],"term":"Pulmonary edema"},{"assessmentType":"SYSTEMATIC_ASSESSMENT","organSystem":"Cardiac disorders","stats":[{"groupId":"EG000","numAffected":1,"numAtRisk":107,"numEvents":1}],"term":"cardiac left ventricular function"},{"assessmentType":"SYSTEMATIC_ASSESSMENT","notes":"Acute respiratory distress syndrome","organSystem":"Respiratory, thoracic and mediastinal disorders","stats":[{"groupId":"EG000","numAffected":1,"numAtRisk":107,"numEvents":1}],"term":"ARDS"},{"assessmentType":"SYSTEMATIC_ASSESSMENT","organSystem":"Respiratory, thoracic and mediastinal disorders","stats":[{"groupId":"EG000","numAffected":1,"numAtRisk":107,"numEvents":1}],"term":"radiation pneumonitis"}]}