{"classes":[{"categories":[{"measurements":[{"groupId":"OG000","spread":"5.801341","value":"17.9"},{"groupId":"OG001","spread":"6.946222","value":"15.75"},{"groupId":"OG002","spread":"3","value":"13"},{"groupId":"OG003","spread":"4.573474","value":"18.25"},{"groupId":"OG004","spread":"5.237684","value":"13.9"},{"groupId":"OG005","spread":"0.707107","value":"10.5"}]}]}],"denoms":[{"counts":[{"groupId":"OG000","value":"10"},{"groupId":"OG001","value":"4"},{"groupId":"OG002","value":"3"},{"groupId":"OG003","value":"4"},{"groupId":"OG004","value":"10"},{"groupId":"OG005","value":"2"}],"units":"Participants"}],"description":"Number of days that patients take to reach engraftment defined as time to hematologic engraftment will be defined as ANC \\>500/µl and platelets \\>20K/µl without transfusion support.","dispersionType":"Standard Deviation","groups":[{"description":"Patients receive cytarabine 3.0gm/M² IV over 1 hour twice daily on days -9 to -7 and cyclophosphamide 45mg/kg IV over 2 hours on days -6 and -5. Patients also undergo total body irradiation (TBI), 165 cGY, twice daily on days -4 to -1 for a total of 1320 cGY.","id":"OG000","title":"Regimen A"},{"description":"Patients receive cyclophosphamide 60 mg/kg IV on days -6 and -5. Patients also undergo total body irradiation (TBI) twice daily on days -4 to -1 for a total of 1320 cGY..","id":"OG001","title":"Regimen B-1"},{"description":"Patients receive cyclophosphamide 60 mg/kg IV over 2 hours on days -5 and -4. Patients also undergo TBI twice daily on days -3 to -1 for a total of 1200 cGY.","id":"OG002","title":"Regimen B-2"},{"description":"Patients undergo total body irradiation (TBI) twice daily on days -7 to -5 for a total of 1200 cGY. Patients then receive cyclophosphamide 60 mg/kg IV on days -4 and -3.","id":"OG003","title":"Regimen B-3"},{"description":"Patients receive oral busulfan 1mg/kg/dose (or 40mg/m2/dose for young children)4 times daily on days -8 to -5 and cyclophosphamide 60 mg/kg IV over 2 hours on days -4 to -2.","id":"OG004","title":"Regimen C"},{"description":"Patients receive total body irradiation (TBI) on days T -6, -5 and -4 for a total of 1320 cGy , then etoposide (60mg/kg/dose) on day -3.","id":"OG005","title":"Regimen D"}],"paramType":"MEAN","reportingStatus":"POSTED","timeFrame":"at day 42","title":"Rates of Durable Engraftment","type":"PRIMARY","unitOfMeasure":"days"}