{"groups":[{"description":"Patients receive leucovorin calcium (LV) IV (20 mg/m\\^2 per day) and fluorouracil (5-FU) IV (425 mg/m\\^2 per day) on days 1-5 of courses 1, 3, and 4. Courses repeat every 28 days. During course 2, patients undergo radiotherapy 5 days a week and receive 5-FU IV continuously for 5 to 6 weeks. Patients rest for 28-35 days between course 2 and 3.","id":"FG000","title":"Arm I (5-FU/LV)"},{"description":"Patients receive epirubicin IV (50 mg/m\\^2) over 3-15 minutes and cisplatin IV (60 mg/m\\^2) over 1 hour on day 1 and 5-FU IV (200 mg/m\\^2 per day) continuously on days 1-21 during course 1. Beginning 1 week later, patients undergo radiotherapy 5 days a week and 5-FU IV continuously for 5 weeks. Patients rest for 28-35 days before beginning course 2 of chemotherapy. Patients then receive epirubicin, cisplatin, and 5-FU as in course 1. Treatment repeats every 21 days for 2 courses.","id":"FG001","title":"Arm II (ECF)"}],"periods":[{"milestones":[{"achievements":[{"groupId":"FG000","numSubjects":"280"},{"groupId":"FG001","numSubjects":"266"}],"type":"STARTED"},{"achievements":[{"groupId":"FG000","numSubjects":"280"},{"groupId":"FG001","numSubjects":"266"}],"type":"COMPLETED"},{"achievements":[{"groupId":"FG000","numSubjects":"0"},{"groupId":"FG001","numSubjects":"0"}],"type":"NOT COMPLETED"}],"title":"Overall Study"}]}