{"denoms":[{"counts":[{"groupId":"BG000","value":"280"},{"groupId":"BG001","value":"266"},{"groupId":"BG002","value":"546"}],"units":"Participants"}],"groups":[{"description":"Patients receive leucovorin calcium (LV) IV (20 mg/m\\^2 per day) and fluorouracil (5-FU) IV (425 mg/m\\^2 per day) on days 1-5 of courses 1, 3, and 4. Courses repeat every 28 days. During course 2, patients undergo radiotherapy 5 days a week and receive 5-FU IV continuously for 5 to 6 weeks. Patients rest for 28-35 days between course 2 and 3.","id":"BG000","title":"Arm I (5-FU/LV)"},{"description":"Patients receive epirubicin IV (50 mg/m\\^2) over 3-15 minutes and cisplatin IV (60 mg/m\\^2) over 1 hour on day 1 and 5-FU IV (200 mg/m\\^2 per day) continuously on days 1-21 during course 1. Beginning 1 week later, patients undergo radiotherapy 5 days a week and 5-FU IV continuously for 5 weeks. Patients rest for 28-35 days before beginning course 2 of chemotherapy. Patients then receive epirubicin, cisplatin, and 5-FU as in course 1. Treatment repeats every 21 days for 2 courses.","id":"BG001","title":"Arm II (ECF)"},{"description":"Total of all reporting groups","id":"BG002","title":"Total"}],"measures":[{"classes":[{"categories":[{"measurements":[{"groupId":"BG000","lowerLimit":"23","upperLimit":"81","value":"59"},{"groupId":"BG001","lowerLimit":"29","upperLimit":"83","value":"58"},{"groupId":"BG002","lowerLimit":"23","upperLimit":"83","value":"58.6"}]}]}],"dispersionType":"FULL_RANGE","paramType":"MEDIAN","title":"Age, Continuous","unitOfMeasure":"years"},{"classes":[{"categories":[{"measurements":[{"groupId":"BG000","value":"87"},{"groupId":"BG001","value":"88"},{"groupId":"BG002","value":"175"}],"title":"Female"},{"measurements":[{"groupId":"BG000","value":"193"},{"groupId":"BG001","value":"178"},{"groupId":"BG002","value":"371"}],"title":"Male"}]}],"paramType":"COUNT_OF_PARTICIPANTS","title":"Sex: Female, Male","unitOfMeasure":"Participants"},{"classes":[{"categories":[{"measurements":[{"groupId":"BG000","value":"21"},{"groupId":"BG001","value":"17"},{"groupId":"BG002","value":"38"}]}],"title":"Canada"},{"categories":[{"measurements":[{"groupId":"BG000","value":"259"},{"groupId":"BG001","value":"249"},{"groupId":"BG002","value":"508"}]}],"title":"United States"}],"paramType":"NUMBER","title":"Region of Enrollment","unitOfMeasure":"participants"}]}