{"analyses":[{"groupDescription":"Two hundred and fifty-two patients (126/arm) provide at least 86% power to detect a difference of 7 (standard deviation 18) between arms with a two-sided significance level of 0.05.","groupIds":["OG000","OG001"],"nonInferiorityType":"SUPERIORITY","pValue":"0.43","pValueComment":"Two-sided significance level = 0.05","statisticalMethod":"t-test, 2 sided"}],"classes":[{"categories":[{"measurements":[{"groupId":"OG000","spread":"1.18","value":"90.48"},{"groupId":"OG001","spread":"1.11","value":"91.77"}]}]}],"denoms":[{"counts":[{"groupId":"OG000","value":"142"},{"groupId":"OG001","value":"145"}],"units":"Participants"}],"description":"The Performance Status Scale for Head and Neck Cancer (PSS-HN) is a clinician-rated evaluation conducted as an unstructured interview format that assesses three functions: Normalcy of Diet , Public Eating, and Understandability of Speech (this outcome measure). Each function is scored from 0 to 100 and analyzed separately. Higher scores indicate better performance status. Treatment effect was analyzed as time-weighted average between baseline (pretreatment) and one year calculated by use of area under the curve (AUC).","dispersionType":"Standard Error","groups":[{"description":"Standard fractionation radiation therapy with concurrent cisplatin followed by conventional surgery for select patients.","id":"OG000","title":"Standard Fractionation RT + Cisplatin"},{"description":"Accelerated fractionation radiation therapy by concomitant boost with concurrent cisplatin followed by conventional surgery for select patients.","id":"OG001","title":"Accelerated Fractionation RT + Cisplatin"}],"paramType":"MEAN","populationDescription":"Eligible patients who did not withdraw consent, with all 4 assessments: baseline, last 2 weeks of treatment, 3 months, and 12 months.","reportingStatus":"POSTED","timeFrame":"Baseline (pretreatment), sometime during the last two weeks of treatment, three months from start of treatment, and one year from start of treatment.","title":"PSS-HN Understandability of Speech Score - AUC at One Year","type":"SECONDARY","unitOfMeasure":"score on a scale * months"}