{"classes":[{"categories":[{"measurements":[{"groupId":"OG000","lowerLimit":"76.2","upperLimit":"81.5","value":"78.9"},{"groupId":"OG001","lowerLimit":"83.8","upperLimit":"88.2","value":"86.0"},{"groupId":"OG002","lowerLimit":"81.0","upperLimit":"85.8","value":"83.4"}]}]}],"denoms":[{"counts":[{"groupId":"OG000","value":"1073"},{"groupId":"OG001","value":"1074"},{"groupId":"OG002","value":"1075"}],"units":"Participants"}],"description":"Overall survival of the participants was measured from the date of randomization up to the date of death due to any cause. Overall survival was estimated using the Kaplan-Meier method.","dispersionType":"95% Confidence Interval","groups":[{"description":"Doxorubicin 60 mg/m² IV bolus injection in combination with cyclophosphamide 600 mg/m² IV bolus injection on Day 1 of every 3 weeks for 4 cycles followed by docetaxel 100 mg/m² IV infusion every 3 weeks for another 4 cycles.","id":"OG000","title":"Doxorubicin+Cyclophosphamide (AC) Followed by Docetaxel (AC→T)"},{"description":"Doxorubicin 60 mg/m² IV bolus injection in combination with cyclophosphamide 600 mg/m² IV bolus Injection on Day 1 of every 3 weeks for 4 cycles. Herceptin 4 mg/kg IV infusion on Day 1 of Cycle 5, followed by Herceptin 2 mg/kg by IV infusion weekly starting from Day 8; and docetaxel 100 mg/m² IV infusion on Day 2 of Cycle 5, then on Day 1 of every 3 weeks for all subsequent cycles ( total 4 cycles). After completion of the last cycle of chemotherapy, Herceptin 6 mg/kg IV infusion was administered every 3 weeks until 1 year from date of initial Herceptin dose.","id":"OG001","title":"AC Followed by Docetaxel + Herceptin (AC→TH)"},{"description":"Herceptin 4 mg/kg IV infusion on Day 1 of Cycle 1 only, followed by Herceptin 2 mg/kg IV infusion weekly starting from Day 8 until three weeks after the last cycle of chemotherapy. Docetaxel 75 mg/ m² IV infusion on Day 2 of Cycle 1, then on Day 1 of all subsequent cycles followed by carboplatin IV infusion at target AUC = 6 mg/mL/min repeated every 3 weeks for a total of 6 cycles. After completion of the last cycle of chemotherapy, Herceptin 6 mg/kg by IV infusion was administered every 3 weeks until 1 year from date of initial Herceptin dose.","id":"OG002","title":"Docetaxel + Carboplatin + Herceptin (TCH)"}],"paramType":"NUMBER","populationDescription":"ITT population.","reportingStatus":"POSTED","timeFrame":"From randomization until death or up to 10 years","title":"Overall Survival- Percentage of Participants Who Survived at 10 Years","type":"SECONDARY","unitOfMeasure":"percentage of particpants"}