{"classes":[{"categories":[{"measurements":[{"groupId":"OG000","value":"327"},{"groupId":"OG001","value":"333"}]}],"title":"Alanine transaminase"},{"categories":[{"measurements":[{"groupId":"OG000","value":"300"},{"groupId":"OG001","value":"288"}]}],"title":"Aspartate aminotransferase"},{"categories":[{"measurements":[{"groupId":"OG000","value":"334"},{"groupId":"OG001","value":"289"}]}],"title":"Alkaline Phosphatase"},{"categories":[{"measurements":[{"groupId":"OG000","value":"67"},{"groupId":"OG001","value":"68"}]}],"title":"Calcium (Hyper)"},{"categories":[{"measurements":[{"groupId":"OG000","value":"150"},{"groupId":"OG001","value":"112"}]}],"title":"Calcium (Hypo)"},{"categories":[{"measurements":[{"groupId":"OG000","value":"20"},{"groupId":"OG001","value":"43"}]}],"title":"Granulocytes"},{"categories":[{"measurements":[{"groupId":"OG000","value":"691"},{"groupId":"OG001","value":"650"}]}],"title":"Hemoglobin"},{"categories":[{"measurements":[{"groupId":"OG000","value":"778"},{"groupId":"OG001","value":"744"}]}],"title":"Lymphocytes"},{"categories":[{"measurements":[{"groupId":"OG000","value":"308"},{"groupId":"OG001","value":"596"}]}],"title":"Neutrophils"},{"categories":[{"measurements":[{"groupId":"OG000","value":"316"},{"groupId":"OG001","value":"612"}]}],"title":"Neutrophils/Granulocytes"},{"categories":[{"measurements":[{"groupId":"OG000","value":"182"},{"groupId":"OG001","value":"160"}]}],"title":"Platelets"},{"categories":[{"measurements":[{"groupId":"OG000","value":"209"},{"groupId":"OG001","value":"156"}]}],"title":"Potassium"},{"categories":[{"measurements":[{"groupId":"OG000","value":"157"},{"groupId":"OG001","value":"138"}]}],"title":"Serum Creatinine"},{"categories":[{"measurements":[{"groupId":"OG000","value":"189"},{"groupId":"OG001","value":"184"}]}],"title":"Sodium"},{"categories":[{"measurements":[{"groupId":"OG000","value":"501"},{"groupId":"OG001","value":"185"}]}],"title":"Total Bilirubin"},{"categories":[{"measurements":[{"groupId":"OG000","value":"220"},{"groupId":"OG001","value":"409"}]}],"title":"White blood cell"}],"denoms":[{"counts":[{"groupId":"OG000","value":"995"},{"groupId":"OG001","value":"974"}],"units":"Participants"}],"description":"Laboratory abnormalities were categorized according to the National Cancer Institute of Canada Common Toxicity Criteria (NCIC - CTC) grading system (May 1991 revised) as Grade 1 (mild), Grade 2 (moderate), Grade 3 (severe) and Grade 4 (life- threatening). Participants with abnormalities in hemoglobin, granulocytes, lymphocytes, neutrophils, neutrophils/granulocytes, platelets, white blood cell, potassium, serum creatinine, sodium, total bilirubin, alanine transaminase, aspartate aminotransferase, alkaline phosphatase, calcium (hyper), and calcium (hypo) with Grades 1-4 were presented.","groups":[{"description":"Participants received capecitabine 1250 (mg/m \\^ 2) orally, twice a day, for 14 days, followed by a 7-day rest period without treatment, as an intermittent therapy in a 3-week cycle for 8 cycles (24 weeks).","id":"OG000","title":"Capecitabine"},{"description":"Participants received leucovorin 20 mg/m \\^ 2 followed by 5-fluorouracil at 425 mg/m \\^ 2, by rapid intravenous injection, daily, from Days 1 to 5 of the first week in each 4-week cycle for 6 cycles (24 weeks).","id":"OG001","title":"5-Fluorouracil + Leucovorin"}],"paramType":"NUMBER","populationDescription":"The safety population comprises all participants who received at least one dose of capecitabine, 5-fluorouracil, or leucovorin and had at least one post baseline safety assessment.","reportingStatus":"POSTED","timeFrame":"Up to Week 25","title":"Number of Participants With Abnormalities for Blood Chemistry and Hematological Parameters","type":"SECONDARY","unitOfMeasure":"Participants"}