{"eventGroups":[{"description":"ciprofloxacin: Begin oral ciprofloxacin when they start chemotherapy for multiple myeloma. Assigned treatment consists of ciprofloxacin (Cipro® 500 mg po tablet every 12 hours for two months. The patient will continue to be observed one additional month on study continuing regular myeloma chemotherapy.\n\nofloxacin: Begin oral ofloxacin when they start chemotherapy for multiple myeloma. Assigned treatment consists of ofloxacin (500 mg po tablet every 12 hours for two months. The patient will continue to be observed one additional month on study continuing regular myeloma chemotherapy.","id":"EG000","otherNumAffected":1,"otherNumAtRisk":69,"seriousNumAffected":1,"seriousNumAtRisk":69,"title":"Ciprofloxacin or Ofloxacin"},{"description":"trimethoprim-sulfamethoxazole: Begin oral Trimethoprim-sulfamethoxazole when they start chemotherapy for multiple myeloma. Assigned treatment consists of TMP-SMX (Septra® or Bactrim®) 1 DS tablet \\[TMP-SMX DS = 160 mg trimethoprim and 800 mg sulfamethoxazole\\] every 12 hours for two months..","id":"EG001","otherNumAffected":1,"otherNumAtRisk":76,"seriousNumAffected":2,"seriousNumAtRisk":76,"title":"TMP-SMX"},{"description":"No Prophylaxis: The patient will receive no prophylactic antibiotics.","id":"EG002","otherNumAffected":0,"otherNumAtRisk":67,"seriousNumAffected":0,"seriousNumAtRisk":67,"title":"Observation"}],"frequencyThreshold":"0","otherEvents":[{"assessmentType":"SYSTEMATIC_ASSESSMENT","organSystem":"Infections and infestations","stats":[{"groupId":"EG000","numAffected":0,"numAtRisk":69},{"groupId":"EG001","numAffected":1,"numAtRisk":76},{"groupId":"EG002","numAffected":0,"numAtRisk":67}],"term":"Thrush"},{"assessmentType":"SYSTEMATIC_ASSESSMENT","notes":"Hospitalized with GI bleed","organSystem":"Gastrointestinal disorders","stats":[{"groupId":"EG000","numAffected":1,"numAtRisk":69},{"groupId":"EG001","numAffected":0,"numAtRisk":76},{"groupId":"EG002","numAffected":0,"numAtRisk":67}],"term":"GI bleed"}],"seriousEvents":[{"assessmentType":"SYSTEMATIC_ASSESSMENT","notes":"Hospitalized for evaluation of pain, shortness of breath, cough; death","organSystem":"General disorders","stats":[{"groupId":"EG000","numAffected":1,"numAtRisk":69},{"groupId":"EG001","numAffected":0,"numAtRisk":76},{"groupId":"EG002","numAffected":0,"numAtRisk":67}],"term":"Death"},{"assessmentType":"SYSTEMATIC_ASSESSMENT","notes":"Hospitalized for acute renal failure","organSystem":"Renal and urinary disorders","stats":[{"groupId":"EG000","numAffected":0,"numAtRisk":69},{"groupId":"EG001","numAffected":1,"numAtRisk":76},{"groupId":"EG002","numAffected":0,"numAtRisk":67}],"term":"Renal failure"},{"assessmentType":"SYSTEMATIC_ASSESSMENT","notes":"Hospitalized for bacterial infection, oral thrush, allergic reaction to sulfa","organSystem":"Infections and infestations","stats":[{"groupId":"EG000","numAffected":0,"numAtRisk":69},{"groupId":"EG001","numAffected":1,"numAtRisk":76},{"groupId":"EG002","numAffected":0,"numAtRisk":67}],"term":"Infection, thrush, allergic reaction"}],"timeFrame":"Three months."}